TSPAN8 and PNLIPRP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSPAN8	PNLIPRP1
Description		tetraspanin 8	pancreatic lipase related protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome	Extracellular Region Extracellular Space
	Molecular Function	Integrin Binding Protein Binding	Triglyceride Lipase Activity Calcium Ion Binding Protein Binding Lipase Activity
	Biological Process	Spermatogenesis Regulation Of Gene Expression Negative Regulation Of Blood Coagulation	Lipid Metabolic Process
Pathways			Digestion of dietary lipid
Drugs
Diseases
GWAS		Asthma ( 34103634 32296059) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Medication use (adrenergics, inhalants) ( 31015401) Monobrow ( 27182965) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Type 2 diabetes ( 22885922 18372903 30054458 29358691 30297969 32499647 20581827 28869590) Upper eyelid sagging severity ( 24869959)	Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)
Interacting Genes		5 interacting genes: PNLIPRP1 PTCH1 SLC38A7 STX2 TIMM23	43 interacting genes: AQP2 BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 PITRM1 RETREG3 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35C2 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8
Entrez ID		7103	5407
HPRD ID		02865	05109
Ensembl ID		ENSG00000127324	ENSG00000187021
Uniprot IDs		P19075	P54315
PDB IDs			2PPL
Enriched GO Terms of Interacting Partners?
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