PNLIPRP1 and TSPAN8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PNLIPRP1	TSPAN8
Description		pancreatic lipase related protein 1	tetraspanin 8
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome
	Molecular Function	Triglyceride Lipase Activity Calcium Ion Binding Protein Binding Lipase Activity	Integrin Binding Protein Binding
	Biological Process	Lipid Metabolic Process	Spermatogenesis Regulation Of Gene Expression Negative Regulation Of Blood Coagulation
Pathways		Digestion of dietary lipid
Drugs
Diseases
GWAS		Anger ( 24489884) Blood protein levels ( 30072576) Body mass index ( 26426971) Loneliness ( 27629369) Loneliness (linear analysis) ( 27629369) Loneliness (multivariate analysis) ( 27629369)	Asthma ( 34103634 32296059) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Medication use (adrenergics, inhalants) ( 31015401) Monobrow ( 27182965) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Type 2 diabetes ( 22885922 18372903 30054458 29358691 30297969 32499647 20581827 28869590) Upper eyelid sagging severity ( 24869959)
Interacting Genes		43 interacting genes: AQP2 BEST2 CD79A CERS4 CPLX4 CREB3 CYB5R3 EBP FAM209A FFAR2 GDAP1 GJA8 GJB5 GPR152 GPR42 GPX8 HSD17B13 KCNJ6 LEUTX LMNA LRRC25 MCFD2 MEOX2 MUC1 NDUFAF1 NEMP1 PEX12 PITRM1 RETREG3 SLC10A6 SLC16A2 SLC18A1 SLC34A2 SLC35C2 SLC39A2 SLC7A1 STX1A TMEM14B TMEM237 TMEM31 TMPPE TMX2 TSPAN8	5 interacting genes: PNLIPRP1 PTCH1 SLC38A7 STX2 TIMM23
Entrez ID		5407	7103
HPRD ID		05109	02865
Ensembl ID		ENSG00000187021	ENSG00000127324
Uniprot IDs		P54315	P19075
PDB IDs		2PPL
Enriched GO Terms of Interacting Partners?
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