TSPAN8 and TIMM23

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TSPAN8	TIMM23
Description		tetraspanin 8	translocase of inner mitochondrial membrane 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Integrin Binding Protein Binding	Protein Binding Protein Transmembrane Transporter Activity
	Biological Process	Spermatogenesis Regulation Of Gene Expression Negative Regulation Of Blood Coagulation	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix
Pathways			Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Asthma ( 34103634 32296059) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Medication use (adrenergics, inhalants) ( 31015401) Monobrow ( 27182965) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Type 2 diabetes ( 22885922 18372903 30054458 29358691 30297969 32499647 20581827 28869590) Upper eyelid sagging severity ( 24869959)	Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) Prostate cancer ( 25939597 27262462)
Interacting Genes		5 interacting genes: PNLIPRP1 PTCH1 SLC38A7 STX2 TIMM23	17 interacting genes: AQP6 CREB3L1 EBP FAM210B FXYD3 GOLT1A HSD17B13 JAGN1 RNASEK SCN3B SLC16A7 TIMM17B TLCD4 TMEM14B TMEM86B TMEM88 TSPAN8
Entrez ID		7103	100287932
HPRD ID		02865
Ensembl ID		ENSG00000127324	ENSG00000265354
Uniprot IDs		P19075	O14925
PDB IDs
Enriched GO Terms of Interacting Partners?
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