TAF4 and CBX3

Number of citations of the paper that reports this interaction (PubMedID 11959914)
26

Data Source:
HPRD (in vitro, two hybrid)

		TAF4	CBX3
Description		TATA-box binding protein associated factor 4	chromobox 3
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex MLL1 Complex	Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Euchromatin Heterochromatin Nucleus Nuclear Envelope Nuclear Inner Membrane Nucleoplasm Pericentric Heterochromatin Spindle RNA Polymerase II Transcription Regulator Complex Site Of DNA Damage
	Molecular Function	Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity	Transcription Coregulator Binding Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter	Chromatin Remodeling Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Promoter Escape Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Body mass index ( 28892062) Fasting glucose ( 33381925) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Systolic blood pressure ( 33230300)	Metabolite levels ( 23823483) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		22 interacting genes: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 H3-4 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12	44 interacting genes: ADAMTSL4 ADNP2 ARL5A ATXN7L2 AURKA AURKB BARD1 CACNB4 CBX1 CBX5 CDC42 DNMT3B DSN1 GDF15 H1-4 H3-4 H3C1 H4C1 HECW2 HIPK2 HTR2C KLF11 L3MBTL1 LAP3 LBR LIG1 MGA MIS12 MKI67 MRPL12 NSD3 PIM1 PRR14 RAD54L2 SP100 STK16 TAF4 TRIM24 TRIM28 VHL ZNF10 ZNF280C ZNF280D ZNF496
Entrez ID		6874	11335
HPRD ID		11797	05130
Ensembl ID		ENSG00000130699	ENSG00000122565
Uniprot IDs		O00268	A4D177 Q13185
PDB IDs		1H3O 2P6V 6MZC 6MZD 6MZL 6MZM	2L11 3DM1 3KUP 3TZD 5T1I 6HW2
Enriched GO Terms of Interacting Partners?
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