Description |
SRC proto-oncogene, non-receptor tyrosine kinase |
androgen receptor |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Diethylstilbestrol
- Levonorgestrel
- Progesterone
- Spironolactone
- Flutamide
- Oxandrolone
- Fluphenazine
- Testosterone
- Mitotane
- Estrone
- Nilutamide
- Tamoxifen
- Norethisterone
- Drostanolone
- Norgestimate
- Nandrolone phenpropionate
- Ketoconazole
- Acetophenazine
- Bicalutamide
- Fluoxymesterone
- Drospirenone
- Danazol
- Testosterone propionate
- Oxybenzone
- 1-Testosterone
- Boldenone
- Calusterone
- Periciazine
- Prasterone
- Flufenamic acid
- Stanolone
- (R)-Bicalutamide
- Metribolone
- (3AALPHA,4ALPHA,7ALPHA,7AALPHA)- 3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE
- Cyproterone acetate
- LGD2941
- Dimethylcurcumin
- Oxymetholone
- Methyltestosterone
- Norelgestromin
- Stanozolol
- Tetrahydrogestrinone
- (2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)-2-hydroxy-2-methylpropanamide
- BMS-564929
- S-23
- phenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile
- (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide
- Andarine
- (R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
- (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE
- S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE
- 1-TERT-BUTYL-3-(2,5-DIMETHYLBENZYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
- 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE
- 2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-methylbenzonitrile
- LGD-2226
- 3-[(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)METHYL]PHENOL
- Triclosan
- Nandrolone decanoate
- Ulipristal
- Enzalutamide
- Eugenol
- Dienogest
- Norethynodrel
- Norgestrel
- Homosalate
- Enzacamene
- Mibolerone
- Phenothiazine
- Gestrinone
- Apalutamide
- Clascoterone
- Darolutamide
- Esculin
- Ligandrol
- Testosterone cypionate
- Testosterone enanthate
- Testosterone undecanoate
- Stanolone acetate
- Segesterone acetate
- Boldenone undecylenate
- Echinacoside
- Ketodarolutamide
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Diseases |
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GWAS |
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Interacting Genes |
310 interacting genes:
ABL1
ACTN1
ADAM12
ADAM15
ADRB2
ADRB3
AFAP1
AFAP1L2
AGAP1
AKT1
ALDOB
ANKRD11
ANXA1
ANXA2
ANXA7
AR
ARHGAP1
ARHGAP17
ARHGAP32
ARHGAP35
ARR3
ASAP1
ATG9A
ATP2B4
AXL
BAAT
BARD1
BCAR1
BCCIP
BCR
BMX
CA3
CASP8
CAV1
CAV2
CBL
CBLC
CCDC180
CCNA1
CD2AP
CD33
CD36
CD44
CD46
CD59
CDC25A
CDC37
CDCP1
CDH5
CDK1
CDK5
CDKN1B
CEACAM1
CEACAM3
CFL1
CHUK
CLTC
CNTNAP1
COASY
CORO7
CRMP1
CSK
CTNNB1
CTNND1
CTSV
CTTN
CUL4B
DAB1
DAB2
DAG1
DAPP1
DDR2
DGKA
DGKZ
DLG4
DNM1
DNM2
DOK1
DOK2
DOK4
DPYD
EFNA5
EFNB1
EFNB2
EFS
EGFR
EGLN1
EMD
ENO1
ENPP7
EPHA3
EPHA4
EPHB2
EPS8
ERBB2
ERBB3
ERBB4
ERRFI1
ESR1
ESR2
ETS1
ETS2
EVL
FANCC
FARP2
FASLG
FBP2
FBXO5
FGR
FHIT
FLNA
FLT3
FMR1
FOXO1
FRS2
FYB1
FZR1
GAB1
GAB2
GAB3
GALNT12
GFAP
GIT1
GJA1
GJB1
GRB10
GRB2
GRIN2A
GRIN2B
GRK2
GTF2I
GUCY2C
HDAC3
HEMGN
HLA-A
HLA-B
HNF1A
HNRNPK
HRAS
HSP90AA1
IGF1R
IKBKB
IKBKG
IL6R
INPPL1
INSR
ITGB3
ITK
JUP
KCNA5
KCNB1
KCNQ5
KDR
KHDRBS1
KIFAP3
KIT
LRP1
LYN
MAP2
MAP2K1
MAPK15
MAPK3
MAPK8IP3
MAPRE1
MAPT
MATK
MDM2
MED28
MET
MICAL1
MPZL1
MST1R
MT-ND2
MUC1
MYLK
NANS
NCOA6
NEDD4
NFKBIA
NMT1
NOS2
NPHS1
NR1I2
NR1I3
NR3C1
P2RY2
PAK2
PDCD6IP
PDE4D
PDE6G
PDGFRB
PDPK1
PECAM1
PELP1
PGR
PI3
PIK3R1
PIK3R3
PIP5K1C
PKD1
PLCG1
PLD1
PLD2
PLSCR1
PLTP
PPARD
PPARGC1B
PPP2CB
PRKACA
PRKCA
PRKCD
PRKCE
PRKCH
PRKCI
PRKCZ
PRKD1
PROM1
PTK2
PTK2B
PTPA
PTPN1
PTPN11
PTPN18
PTPN2
PTPN21
PTPN6
PTPRA
PTPRC
PTPRE
PTPRT
PXN
RACK1
RAF1
RARA
RASA1
RASGRF1
RET
RGS16
RPL10
RPS6KA3
RPS6KB1
RPS6KB2
RXRA
SH2D3C
SH3BP1
SH3PXD2A
SHB
SHC1
SKAP1
SKAP2
SLC9A2
SMARCB1
SMARCE1
SNCA
SOCS1
SORBS1
SPTAN1
SRCIN1
SRF
SRPK2
STAP2
STAT1
STAT3
STAT5A
STAT5B
STAT6
STUB1
STX17
SYK
SYN1
TAMALIN
TERT
THRA
THRB
TIAM1
TMPO
TNFRSF11A
TNFRSF1A
TNK2
TP53
TRAF1
TRAF3
TRAF6
TRAT1
TRIM50
TRIM7
TRIP10
TRIP6
TRMO
TRPC6
TRPV4
TUB
TXK
TYRO3
USP8
VCL
VDR
VIL1
WAS
WASL
WBP11
WWOX
XPA
YTHDC1
YWHAB
YWHAE
YWHAG
YWHAH
ZNF189
ZNF687
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265 interacting genes:
ABL1
ABL2
ACTB
AHR
AKT1
APOL2
APPBP2
ARID5A
ATF2
BAG1
BLK
BLNK
BRCA1
BTK
CACUL1
CALM1
CALR
CASP1
CASP3
CASP7
CASP8
CAV1
CCAR2
CCND1
CCNE1
CCNH
CDC25A
CDC25B
CDC37
CDK1
CDK6
CDK7
CDK9
CEBPA
CEBPB
CHD8
COX5B
CREBBP
CRK
CTDSP2
CTNNB1
CUL4B
DAP3
DAXX
DCAF6
DCC
DDB2
DDC
DENND5A
EED
EFCAB6
EGFR
ELF3
EP300
ERCC2
ERCC3
ESR1
ETV5
EZH2
FES
FGR
FHL2
FLNA
FOXA1
FOXG1
FOXO1
GADD45GIP1
GAK
GAPDH
GLI2
GRAP2
GRB2
GRB7
GRIP1
GSK3B
GSN
GTF2F1
GTF2F2
GTF2H1
GTF2H2
GTF2H3
HCK
HDAC1
HDAC3
HDAC4
HIF1A
HIPK3
HMGB1
HMGB2
HOTAIR
HSH2D
HSP90AA1
IARS1
IDE
IFI16
IL6ST
INPPL1
JMJD1C
JUN
KAT2B
KAT5
KAT7
KDM1A
KIF15
KIF1A
KIFAP3
KLK2
LCK
LCOR
LYN
MAGEA11
MAPK1
MATK
MDM2
MDN1
MED1
MED12L
MED14
MED24
MLH3
MYBBP1A
MYLIP
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NDE1
NELFCD
NFKB1
NISCH
NLRP10
NONO
NR0B1
NR0B2
NR2C1
NR2C2
NR3C1
NR3C2
NR5A1
NRIP1
NSD1
NSD2
PA2G4
PAK6
PELP1
PGK1
PIAS1
PIAS2
PIAS3
PIAS4
PIK3R1
PIK3R2
PIK3R3
PLCG1
PLCG2
PNRC1
PNRC2
POU2F1
POU2F2
POU5F1
PRKG1
PRMT1
PRPF6
PSMC3IP
PTEN
PTK6
PTPN11
PXN
RAC3
RACK1
RAD54L2
RAD9A
RAF1
RAN
RANBP9
RASA1
RB1
RBAK
RCHY1
REL
RELA
REPS2
RNASEL
RNF14
RNF4
RNF6
RUNX1
RUNX2
SART3
SFPQ
SH2D1A
SH2D1B
SH2D2A
SH2D3C
SH3YL1
SHB
SHC1
SHC3
SHC4
SHE
SIRT1
SLC25A4
SMAD1
SMAD3
SMAD4
SMARCA2
SMARCA4
SMARCD1
SMARCE1
SOCS3
SOCS6
SP1
SPDEF
SPOP
SRC
SREBF1
SRY
STAP1
STAT3
STUB1
SUMO1
SUV39H2
SVIL
SYK
TADA3
TAF1
TBP
TCF20
TCF4
TCF7L2
TDG
TGFB1I1
TGIF1
TLE5
TMF1
TNK2
TNS1
TNS4
TPD52
TRIM24
TRIP4
TSG101
TXNDC5
UBE2I
UBE3A
USP10
UXT
VAV1
VAV2
VAV3
VCP
WIPI1
XRCC5
XRCC6
YES1
YWHAQ
ZBTB1
ZBTB16
ZBTB32
ZMIZ1
ZMIZ2
ZNF451
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Entrez ID |
6714 |
367 |
HPRD ID |
01819 |
02437 |
Ensembl ID |
ENSG00000197122
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ENSG00000169083
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Uniprot IDs |
P12931
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A0A087WUX9
F1D8N5
G4VV16
P10275
Q9NUA2
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PDB IDs |
1A07
1A08
1A09
1A1A
1A1B
1A1C
1A1E
1FMK
1HCS
1HCT
1KSW
1O41
1O42
1O43
1O44
1O45
1O46
1O47
1O48
1O49
1O4A
1O4B
1O4C
1O4D
1O4E
1O4F
1O4G
1O4H
1O4I
1O4J
1O4K
1O4L
1O4M
1O4N
1O4O
1O4P
1O4Q
1O4R
1SHD
1Y57
1YI6
1YOJ
1YOL
1YOM
2BDF
2BDJ
2H8H
2SRC
3VRO
3ZMP
3ZMQ
4F59
4F5A
4F5B
4HXJ
4K11
4MXO
4MXX
4MXY
4MXZ
6ATE
6C4S
6E6E
6EHJ
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1E3G
1GS4
1T5Z
1T63
1T65
1XJ7
1XOW
1XQ3
1Z95
2AM9
2AMA
2AMB
2AO6
2AX6
2AX7
2AX8
2AX9
2AXA
2HVC
2OZ7
2PIO
2PIP
2PIQ
2PIR
2PIT
2PIU
2PIV
2PIW
2PIX
2PKL
2PNU
2Q7I
2Q7J
2Q7K
2Q7L
2YHD
2YLO
2YLP
2YLQ
2Z4J
3B5R
3B65
3B66
3B67
3B68
3BTR
3L3X
3L3Z
3RLJ
3RLL
3V49
3V4A
3ZQT
4HLW
4K7A
4OEA
4OED
4OEY
4OEZ
4OFR
4OFU
4OGH
4OH5
4OH6
4OHA
4OIL
4OIU
4OJ9
4OJB
4OK1
4OKB
4OKT
4OKW
4OKX
4OLM
4QL8
5CJ6
5JJM
5T8E
5T8J
5V8Q
5VO4
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Enriched GO Terms of Interacting Partners? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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