SNAPC3 and HSD17B14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SNAPC3	HSD17B14
Description		small nuclear RNA activating complex polypeptide 3	hydroxysteroid 17-beta dehydrogenase 14
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Body SnRNA-activating Protein Complex	Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding DNA Binding Bent DNA Binding Protein Binding	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Testosterone 17-beta-dehydrogenase (NADP+) Activity
	Biological Process	Transcription By RNA Polymerase II Transcription By RNA Polymerase III SnRNA Transcription SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	Steroid Catabolic Process
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Estrogen biosynthesis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		11 interacting genes: CEP57L1 ENO1 HSD17B14 KATNBL1 NFKBID RB1 SNAPC1 SNRNP35 TTC4 UBE3A ZNF620	24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B
Entrez ID		6619	51171
HPRD ID		03826	16801
Ensembl ID		ENSG00000164975	ENSG00000087076
Uniprot IDs		Q92966	A0A140VJH8 Q9BPX1
PDB IDs			1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK 6ZDE 6ZDI
Enriched GO Terms of Interacting Partners?
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