HSD17B14 and AKIRIN2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSD17B14	AKIRIN2
Description		hydroxysteroid 17-beta dehydrogenase 14	akirin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Chromatin Nucleus Nucleoplasm Transcription Repressor Complex
	Molecular Function	Estradiol 17-beta-dehydrogenase Activity Protein Binding Identical Protein Binding 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Testosterone 17-beta-dehydrogenase (NADP+) Activity	Transcription Coregulator Activity Protein Binding Enzyme Binding Identical Protein Binding
	Biological Process	Steroid Catabolic Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Response To Lipopolysaccharide Positive Regulation Of Interleukin-6 Production Innate Immune Response Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Estrogen biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Resting metabolic rate ( 28476931)
Interacting Genes		24 interacting genes: AKIRIN2 BRIP1 CA8 CDKN2D CYTOR DDIT3 INCA1 MIA3 MIR4435-2HG MPG NEK6 NTAQ1 NUDT18 OTUD3 PGLYRP3 PHF1 PICK1 PIDD1 PSMA1 REL SNAPC3 SNRPC SREK1IP1 TBC1D22B	11 interacting genes: CCDC85B FBXO7 HNRNPF HSD17B14 LNX1 MDN1 MESD MYOZ3 NTAQ1 SORBS3 SPG21
Entrez ID		51171	55122
HPRD ID		16801	12864
Ensembl ID		ENSG00000087076	ENSG00000135334
Uniprot IDs		A0A140VJH8 Q9BPX1	Q53H80 Q9NW35
PDB IDs		1YDE 5EN4 5HS6 5ICM 5ICS 5JS6 5JSF 5L7T 5L7W 5L7Y 5O42 5O43 5O6O 5O6X 5O6Z 5O72 5O7C 6EMM 6FFB 6G4L 6GBT 6GTB 6GTU 6H0M 6HNO 6QCK 6ZDE 6ZDI
Enriched GO Terms of Interacting Partners?
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