LGALS7B and HSPA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LGALS7B	HSPA6
Description		galectin 7B	heat shock protein family A (Hsp70) member 6
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytosol Extracellular Exosome	Extracellular Region Nucleus Cytoplasm Centriole Cytosol Plasma Membrane Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Galactoside Binding Carbohydrate Binding	Protein Binding ATP Binding ATP Hydrolysis Activity Enzyme Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Apoptotic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Gene Expression Negative Regulation Of Interferon-gamma Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Heat Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding Cellular Heat Acclimation
Pathways			Regulation of HSF1-mediated heat shock response Neutrophil degranulation
Drugs		Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Logical memory (immediate recall) in mild cognitive impairment ( 29274321)	Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Blood protein levels ( 28240269) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Helicobacter pylori serologic status ( 23652523) Inflammatory bowel disease ( 28067908 23128233) Offspring birth weight ( 31043758) Ulcerative colitis ( 28067908 21297633)
Interacting Genes		6 interacting genes: HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2	18 interacting genes: ADCK5 AHCYL1 BAG4 C22orf15 CISH COMMD6 CYP4F12 DNAJB4 FCGR2B FLNA KRT222 LGALS7 LGALS7B MPZ PPIB PRAP1 RPA1 TERF1
Entrez ID		653499	3310
HPRD ID		19145	00775
Ensembl ID		ENSG00000178934	ENSG00000173110
Uniprot IDs		P47929	A0A384NKX5 B3KSM6 P17066
PDB IDs		1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S	3FE1
Enriched GO Terms of Interacting Partners?
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