HSPA6 and LGALS7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HSPA6	LGALS7
Description		heat shock protein family A (Hsp70) member 6	galectin 7
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Centriole Cytosol Plasma Membrane Secretory Granule Lumen Extracellular Exosome Blood Microparticle Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding ATP Binding ATP Hydrolysis Activity Enzyme Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding Misfolded Protein Binding
	Biological Process	Response To Unfolded Protein Vesicle-mediated Transport Cellular Response To Heat Cellular Response To Unfolded Protein Protein Refolding Chaperone Cofactor-dependent Protein Refolding Cellular Heat Acclimation
Pathways		Regulation of HSF1-mediated heat shock response Neutrophil degranulation
Drugs			Beta-D-Glucose beta-D-Galactosamine
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Birth weight ( 31043758) Blood protein levels ( 28240269) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Helicobacter pylori serologic status ( 23652523) Inflammatory bowel disease ( 28067908 23128233) Offspring birth weight ( 31043758) Ulcerative colitis ( 28067908 21297633)	Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
Interacting Genes		18 interacting genes: ADCK5 AHCYL1 BAG4 C22orf15 CISH COMMD6 CYP4F12 DNAJB4 FCGR2B FLNA KRT222 LGALS7 LGALS7B MPZ PPIB PRAP1 RPA1 TERF1	8 interacting genes: CA12 CDC42 HSPA6 LSM2 SSBP1 TAB1 TGM5 YAF2
Entrez ID		3310	3963
HPRD ID		00775	09002
Ensembl ID		ENSG00000173110	ENSG00000205076
Uniprot IDs		A0A384NKX5 B3KSM6 P17066	P47929
PDB IDs		3FE1	1BKZ 2GAL 3GAL 3ZXE 3ZXF 4GAL 4UW3 4UW4 4UW5 4UW6 4XBQ 4Y26 5GAL 5H9Q 5H9S
Enriched GO Terms of Interacting Partners?
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