NABP1 and STAT4

		NABP1	STAT4
Description		nucleic acid binding protein 1	signal transducer and activator of transcription 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Site Of Double-strand Break SOSS Complex	Chromatin Nucleoplasm Cytosol
	Molecular Function	DNA Binding Single-stranded DNA Binding RNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Signaling Response To Ionizing Radiation Mitotic G2/M Transition Checkpoint	Regulation Of Transcription By RNA Polymerase II Defense Response Receptor Signaling Pathway Via JAK-STAT Cytokine-mediated Signaling Pathway Regulation Of Cell Population Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Interleukin-20 family signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Interleukin-35 Signalling Interleukin-12 signaling Interleukin-12 signaling Interleukin-23 signaling Interleukin-21 signaling
Drugs
Diseases
GWAS		Colorectal cancer ( 23266556)	Arthritis (juvenile idiopathic) ( 33106285) Autoimmune thyroid disease ( 32581359) Autoimmune traits (pleiotropy) ( 30572963) Behcet's disease ( 23001997 23291587) Celiac disease ( 22057235 25920553 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Eosinophil counts ( 32888494) Gamma glutamyl transferase levels ( 29403010) Generalized epilepsy ( 30531953) Hepatocellular carcinoma in hepatitis B infection ( 23242368) Idiopathic inflammatory myopathy ( 26362759) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Limited cutaneous systemic scleroderma ( 29293537) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Nontyphoidal Salmonella bacteraemia ( 29523850) Primary biliary cholangitis ( 28425483 23000144 21399635 26394269) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 32723749 30423114 30572963 23143596 24390342 20453841 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) SjÃ¶gren's syndrome ( 24097066 24097067 28076899) Systemic lupus erythematosus ( 27399966 24871463 26606652 23273568 33272962 26663301 23053960 26316170 26502338 18204098 21408207 32771030 19165918 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 28314753 24387989 21750679 31672989 33069728 30572963 20383147 29293537 21779181) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Type 1 diabetes ( 34127860) Vitiligo ( 27723757)
Interacting Genes		12 interacting genes: COPS3 DNAH7 KHDRBS2 MKRN3 PURB QKI RBMX REL STAT4 TFCP2 TP53 TRIM7	24 interacting genes: ADRB2 CADM3 CCDC85A CLPP CREBBP CRK DNAH7 HNRNPCP2 IL12RB1 IL12RB2 JUN LY86 MAP2K6 MAPK14 NABP1 NEMP2 NMI PIAS2 PTMS SH2D1B STAT1 STAT3 TMEFF2 ZNF467
Entrez ID		64859	6775
HPRD ID		08009	02779
Ensembl ID		ENSG00000173559	ENSG00000138378
Uniprot IDs		Q96AH0	Q14765
PDB IDs
Enriched GO Terms of Interacting Partners?
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