STAT4 and DNAH7

		STAT4	DNAH7
Description		signal transducer and activator of transcription 4	dynein axonemal heavy chain 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol	Cytosol Axonemal Dynein Complex Microtubule Cilium Dynein Complex Inner Dynein Arm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	Microtubule Motor Activity Calcium Ion Binding ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Defense Response Receptor Signaling Pathway Via JAK-STAT Cytokine-mediated Signaling Pathway Regulation Of Cell Population Proliferation Response To Peptide Hormone Positive Regulation Of Transcription By RNA Polymerase II	Cilium Movement Microtubule-based Movement Inner Dynein Arm Assembly Cilium-dependent Cell Motility
Pathways		Interleukin-20 family signaling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation Interleukin-35 Signalling Interleukin-12 signaling Interleukin-12 signaling Interleukin-23 signaling Interleukin-21 signaling
Drugs
Diseases
GWAS		Arthritis (juvenile idiopathic) ( 33106285) Autoimmune thyroid disease ( 32581359) Autoimmune traits (pleiotropy) ( 30572963) Behcet's disease ( 23001997 23291587) Celiac disease ( 22057235 25920553 30572963) Celiac disease and Rheumatoid arthritis ( 26546613) Celiac disease or Rheumatoid arthritis ( 21383967) Eosinophil counts ( 32888494) Gamma glutamyl transferase levels ( 29403010) Generalized epilepsy ( 30531953) Hepatocellular carcinoma in hepatitis B infection ( 23242368) Idiopathic inflammatory myopathy ( 26362759) Inflammatory bowel disease ( 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Limited cutaneous systemic scleroderma ( 29293537) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244 24076602) Nontyphoidal Salmonella bacteraemia ( 29523850) Primary biliary cholangitis ( 28425483 23000144 21399635 26394269) Primary biliary cirrhosis ( 22961000) Rheumatoid arthritis ( 32723749 30423114 30572963 23143596 24390342 20453841 20453842) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676) SjÃ¶gren's syndrome ( 24097066 24097067 28076899) Systemic lupus erythematosus ( 27399966 24871463 26606652 23273568 33272962 26663301 23053960 26316170 26502338 18204098 21408207 32771030 19165918 28714469 19838193 19838195) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Systemic sclerosis ( 28314753 24387989 21750679 31672989 33069728 30572963 20383147 29293537 21779181) Systemic sclerosis (anti-centromere-positive) ( 29293537) Systemic seropositive rheumatic diseases (Systemic sclerosis or systemic lupus erythematosus or rheumatoid arthritis or idiopathic inflammatory myopathies) ( 30573655) Type 1 diabetes ( 34127860) Vitiligo ( 27723757)	Diastolic blood pressure ( 31469255)
Interacting Genes		24 interacting genes: ADRB2 CADM3 CCDC85A CLPP CREBBP CRK DNAH7 HNRNPCP2 IL12RB1 IL12RB2 JUN LY86 MAP2K6 MAPK14 NABP1 NEMP2 NMI PIAS2 PTMS SH2D1B STAT1 STAT3 TMEFF2 ZNF467	10 interacting genes: CSTF3 METTL21A MIB2 NABP1 NEMP2 SHC1 STAT4 STK17B TMEFF2 UBC
Entrez ID		6775	56171
HPRD ID		02779	10914
Ensembl ID		ENSG00000138378	ENSG00000118997
Uniprot IDs		Q14765	Q8WXX0
PDB IDs			6RZA
Enriched GO Terms of Interacting Partners?
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