SHMT2 and BRCC3

  • Number of citations of the paper that reports this interaction (PubMedID 31253574)
  • 9

SHMT2

BRCC3

Description serine hydroxymethyltransferase 2 BRCA1/BRCA2-containing complex subunit 3
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 28 interacting genes: ABRAXAS2 ACVR1B APP ARL6IP1 BABAM1 BABAM2 BRCC3 CAB39 CFTR CLEC2D CMTM5 COMMD6 CREB3 CSNK2B DUX4 ESR1 FBXO7 KASH5 KMT2D MAL2 NDRG1 NKD2 OGT PPARD PRKAG1 RND1 SCAF11 TUBA1C 12 interacting genes: ANKRD11 BRCA1 FANCG ICOS IFNAR1 NUMA1 SHMT2 SNAPC5 SUMO2 UBC UBE2D1 UIMC1
Entrez ID 6472 79184
HPRD ID 00717 06465
Ensembl ID ENSG00000182199 ENSG00000185515
Uniprot IDs A0A024RB99 B4DJQ3 B4DLV4 P34897 Q5BJF5 Q5HYG8 V9HW06 P46736
PDB IDs 4PVF 5V7I 5X3V 6DK3 6H3C 6M5O 6QVG 6QVL 6R8F 6H3C 6R8F
Enriched GO Terms of Interacting Partners?
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