SHMT2 and CLEC2D

  • Number of citations of the paper that reports this interaction (PubMedID 27107012)
  • 40
  • Data Source:
  • BioGRID (two hybrid)

SHMT2

CLEC2D

Description serine hydroxymethyltransferase 2 C-type lectin domain family 2 member D
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Asthma ( 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Schizophrenia ( 25056061 29483656)
  • Autoimmune thyroid disease ( 32581359)
  • HDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Multiple sclerosis ( 31604244)
Interacting Genes 28 interacting genes: ABRAXAS2 ACVR1B APP ARL6IP1 BABAM1 BABAM2 BRCC3 CAB39 CFTR CLEC2D CMTM5 COMMD6 CREB3 CSNK2B DUX4 ESR1 FBXO7 KASH5 KMT2D MAL2 NDRG1 NKD2 OGT PPARD PRKAG1 RND1 SCAF11 TUBA1C 33 interacting genes: - ADIPOQ ATP6V0C B3GALT5 BRICD5 CD68 CLDN19 CLDN2 CLEC2A CLRN2 CXCL9 DEFB121 ENTPD8 ERMP1 FAM3C FNDC9 GPR42 IL1RL1 KLRB1 KLRC1 LEPROTL1 NKG7 PLLP PLN PLP1 RPRM SEC22A SHMT2 SYT15 TM4SF18 TMEM190 TMEM80 TSPAN4
Entrez ID 6472 29121
HPRD ID 00717 16134
Ensembl ID ENSG00000182199 ENSG00000069493
Uniprot IDs A0A024RB99 B4DJQ3 B4DLV4 P34897 Q5BJF5 Q5HYG8 V9HW06 Q9UHP7 W8JXM2
PDB IDs 4PVF 5V7I 5X3V 6DK3 6H3C 6M5O 6QVG 6QVL 6R8F 4QKG 4QKH 4QKI 4QKJ 4WCO 5MGT
Enriched GO Terms of Interacting Partners?
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