SH3GL2 and ADRB1

  • Number of citations of the paper that reports this interaction (PubMedID 10535961)
  • 30
  • Data Source:
  • HPRD (in vitro, two hybrid, in vivo)

SH3GL2

ADRB1

Description SH3 domain containing GRB2 like 2, endophilin A1 adrenoceptor beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Aspartate aminotransferase levels ( 33547301)
  • Birth weight ( 23202124 31043758 27680694)
  • Blood pressure ( 21909110)
  • Diastolic blood pressure ( 28135244 27841878 28739976 27618452)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Gaucher disease severity ( 22388998)
  • HDL cholesterol levels ( 32203549)
  • High density lipoprotein cholesterol levels ( 29083408)
  • LDL cholesterol levels ( 32203549)
  • Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Platelet distribution width ( 32888494)
  • PR interval ( 32439900)
  • Systolic blood pressure ( 27841878 28739976 27618447 27618452 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Triglyceride levels ( 32203549)
Interacting Genes 53 interacting genes: ACTG1 ADAM15 ADAM19 ADRB1 AMPH APP ARNT2 ATXN2 BIN1 CD2AP CLEC3B DACT1 DLGAP4 DNM1 DNM2 DPPA4 DPYSL4 EGFL6 EMD ERH F13A1 FBXO32 FXR1 GCH1 GSTM3 HLA-DQA1 IGHM IL6 ITCH ITSN1 LCP2 LRRK2 MAP4K3 MAST2 PAK2 PAXIP1 PDCD6IP PPP1R21 PPP6R1 PRR14 SH3GL3 SH3KBP1 SHANK3 SLC17A7 SYNJ1 TCEA2 TERF1 TIAM2 TMEM108 TYMS ZNF219 ZNF580 ZXDC 16 interacting genes: ADRA2A ARRB1 DLG1 DLG4 DLGAP2 GIPC1 GOPC GPRASP1 GPRASP2 GRB2 MAGI2 MAGI3 NOS1 SH3GL2 SH3GL3 SNTA1
Entrez ID 6456 153
HPRD ID 05125 00181
Ensembl ID ENSG00000107295 ENSG00000043591
Uniprot IDs Q7Z376 Q99962 P08588
PDB IDs 1X03 1X04 2D4C 2DBM 2LSQ
Enriched GO Terms of Interacting Partners?
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