SH3GL2 and TIAM2

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 136
  • Data Source:
  • BioGRID (two hybrid)

SH3GL2

TIAM2

Description SH3 domain containing GRB2 like 2, endophilin A1 TIAM Rac1 associated GEF 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309)
  • Asthma ( 31361310)
  • Dimensional psychopathology (Arousal) ( 29496196)
  • Dimensional psychopathology (Negative) ( 29496196)
  • Heel bone mineral density ( 30598549)
  • Lipoprotein (a) levels ( 26377243)
  • Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes 53 interacting genes: ACTG1 ADAM15 ADAM19 ADRB1 AMPH APP ARNT2 ATXN2 BIN1 CD2AP CLEC3B DACT1 DLGAP4 DNM1 DNM2 DPPA4 DPYSL4 EGFL6 EMD ERH F13A1 FBXO32 FXR1 GCH1 GSTM3 HLA-DQA1 IGHM IL6 ITCH ITSN1 LCP2 LRRK2 MAP4K3 MAST2 PAK2 PAXIP1 PDCD6IP PPP1R21 PPP6R1 PRR14 SH3GL3 SH3KBP1 SHANK3 SLC17A7 SYNJ1 TCEA2 TERF1 TIAM2 TMEM108 TYMS ZNF219 ZNF580 ZXDC 9 interacting genes: ANXA7 DISC1 DNM2 H2AX PARD3 SH3GL2 TK1 TNIK UFD1
Entrez ID 6456 26230
HPRD ID 05125 05273
Ensembl ID ENSG00000107295 ENSG00000146426
Uniprot IDs Q7Z376 Q99962 B3KW11 Q8IVF5
PDB IDs 1X03 1X04 2D4C 2DBM
Enriched GO Terms of Interacting Partners?
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