SRSF2 and ZRSR2

Number of citations of the paper that reports this interaction (PubMedID 9237760)
48

Data Source:
HPRD (two hybrid, in vitro)

		SRSF2	ZRSR2
Description		serine and arginine rich splicing factor 2	zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex U2AF Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding	Protein Binding Pre-mRNA 3'-splice Site Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Vitamin E Negative Regulation Of Transcription, DNA-templated	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS
Interacting Genes		34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2	20 interacting genes: APP CCNL1 CLK2 DVL3 KHDC4 LUC7L2 REP15 SDCBP2 SLC2A1 SRPK2 SRRM4 SRSF1 SRSF2 SRSF5 SSX2IP TEPSIN TNFAIP8L1 U2AF1 U2AF2 ZRSR2P1
Entrez ID		6427	8233
HPRD ID		02888	02068
Ensembl ID		ENSG00000161547	ENSG00000169249
Uniprot IDs		A0A024R8U5 Q01130 Q53FN0	Q15696
PDB IDs		2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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