SRSF2 and CCNL1

Number of citations of the paper that reports this interaction (PubMedID 11683997)
29

Data Source:
HPRD (two hybrid, in vitro)

		SRSF2	CCNL1
Description		serine and arginine rich splicing factor 2	cyclin L1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol PML Body Nuclear Speck Interchromatin Granule	Nucleus Nuclear Speck
	Molecular Function	Transcription Corepressor Activity RNA Binding Protein Kinase C Binding Protein Binding Pre-mRNA Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process	Mitotic Cell Cycle Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Vitamin E Negative Regulation Of Transcription, DNA-templated	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Transcription By RNA Polymerase II RNA Processing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Adiponectin levels in pregnancy ( 28317342) Adult body size ( 32376654) Alanine aminotransferase levels ( 33547301) Anthropometric traits in newborns ( 23575227) Birth weight ( 23202124 31453325 31043758 27680694 20372150) Birth weight variance ( 31453325) Body fat percentage variance ( 31453325) Body mass index ( 26426971) circulating leptin levels ( 32917775 26833098) circulating leptin levels adjusted for BMI ( 32917775 26833098) Coronary artery disease ( 33020668) Diabetic retinopathy ( 21441570) Eating disorders ( 22911880) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Menarche (age at onset) ( 25231870) Offspring birth weight ( 31043758) PR interval ( 30046033 32439900) Smoking cessation in chronic obstructive pulmonary disease ( 21685187)
Interacting Genes		34 interacting genes: ADAP1 BARD1 CCNL1 CCNL2 CDK12 CDK6 CEP72 CIR1 CSNK2A1 FUS GEMIN2 GOLGA2 KAT5 KRT31 KRT40 LIG4 LZTS2 NCF1 PRCC SCAF11 SNRNP70 SREK1 SRPK2 SRSF11 SRSF3 SRSF4 TCF4 TRA2B TRIM27 U2AF1 UBQLN4 YTHDC1 ZRANB2 ZRSR2	22 interacting genes: APP APPBP2 C1orf35 CASP8 CDK11A DVL3 FAM133A JMJD6 KRTAP12-2 NKAPD1 PRDM6 PRPF40A RAD51D RNPS1 RSRP1 SAP30BP SORBS3 SREK1IP1 SRSF2 TFIP11 ZRANB1 ZRSR2
Entrez ID		6427	57018
HPRD ID		02888	10814
Ensembl ID		ENSG00000161547	ENSG00000163660
Uniprot IDs		A0A024R8U5 Q01130 Q53FN0	Q9UK58
PDB IDs		2KN4 2LEA 2LEB 2LEC
Enriched GO Terms of Interacting Partners?
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