SCN4A and SNTB2

Number of citations of the paper that reports this interaction (PubMedID 9412493)
100

Data Source:
HPRD (in vivo)

		SCN4A	SNTB2
Description		sodium voltage-gated channel alpha subunit 4	syntrophin beta 2
Image
GO Annotations	Cellular Component	Voltage-gated Sodium Channel Complex Integral Component Of Plasma Membrane Axon	Intracellular Anatomical Structure Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse
	Molecular Function	Voltage-gated Ion Channel Activity Voltage-gated Sodium Channel Activity Protein Binding	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding
	Biological Process	Sodium Ion Transport Muscle Contraction Neuronal Action Potential Regulation Of Ion Transmembrane Transport Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Skeletal Muscle Contraction By Action Potential
Pathways		Interaction between L1 and Ankyrins Phase 0 - rapid depolarisation
Drugs		Ranolazine Topiramate Lidocaine Valproic acid Lamotrigine Carbamazepine Oxcarbazepine Propofol Cocaine Zonisamide Promethazine Flecainide Brivaracetam Tetracaine Amylocaine Propoxycaine Pramocaine Pentoxyverine Parachlorophenol Dichlorobenzyl alcohol Bioallethrin Fish oil
Diseases
GWAS		Height ( 28552196 31562340) Hip circumference adjusted for BMI ( 34021172)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2	16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN
Entrez ID		6329	6645
HPRD ID		04912	02491
Ensembl ID		ENSG00000007314	ENSG00000168807
Uniprot IDs		P35499	A0A024R732 Q13425
PDB IDs		6AGF 6MBA 6MC9	2VRF
Enriched GO Terms of Interacting Partners?
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