SNTB2 and KCNJ12

Number of citations of the paper that reports this interaction (PubMedID 15024025)
68

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		SNTB2	KCNJ12
Description		syntrophin beta 2	potassium inwardly rectifying channel subfamily J member 12
Image			No pdb structure
GO Annotations	Cellular Component	Intracellular Anatomical Structure Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Focal Adhesion Dystrophin-associated Glycoprotein Complex Membrane Transport Vesicle Membrane Protein-containing Complex Synapse	Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Membrane
	Molecular Function	RNA Binding Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding	Inward Rectifier Potassium Channel Activity Protein Binding
	Biological Process		Potassium Ion Transport Muscle Contraction Regulation Of Heart Contraction Regulation Of Ion Transmembrane Transport Protein Homotetramerization Potassium Ion Import Across Plasma Membrane
Pathways			Activation of G protein gated Potassium channels Classical Kir channels Phase 4 - resting membrane potential Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Dofetilide Ranolazine Miconazole Yohimbine Dronedarone Butamben
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287) Logical memory (delayed recall) in normal cognition ( 29274321)	Adult body size ( 32376654) Body mass index ( 28892062 25673413) Height ( 20881960 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-hip ratio ( 25673412)
Interacting Genes		16 interacting genes: ABCA1 ADGRB1 ADRA1D DGKZ DMD DTNA ERBB4 KCNJ12 MAST1 MAST2 PTEN PTPRN SCN4A SCN5A UBC UTRN	18 interacting genes: ABLIM1 APBA1 CASK CAV3 DLG1 DLG2 DLG3 DLG4 DMD DTNA EMD LIN7A LIN7B LIN7C PRKACA SNTA1 SNTB1 SNTB2
Entrez ID		6645	3768
HPRD ID		02491	09083
Ensembl ID		ENSG00000168807	ENSG00000184185
Uniprot IDs		A0A024R732 Q13425	Q14500
PDB IDs		2VRF
Enriched GO Terms of Interacting Partners?
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