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SCN4A

Description sodium voltage-gated channel alpha subunit 4
Image
GO Annotations Cellular Component
  • Voltage-gated Sodium Channel Complex
  • Integral Component Of Plasma Membrane
  • Axon
Molecular Function
  • Voltage-gated Ion Channel Activity
  • Voltage-gated Sodium Channel Activity
  • Protein Binding
Biological Process
  • Sodium Ion Transport
  • Muscle Contraction
  • Neuronal Action Potential
  • Regulation Of Ion Transmembrane Transport
  • Sodium Ion Transmembrane Transport
  • Membrane Depolarization During Action Potential
  • Regulation Of Skeletal Muscle Contraction By Action Potential
Pathways
  • Interaction between L1 and Ankyrins
  • Phase 0 - rapid depolarisation
Drugs
  • Ranolazine
  • Topiramate
  • Lidocaine
  • Valproic acid
  • Lamotrigine
  • Carbamazepine
  • Oxcarbazepine
  • Propofol
  • Cocaine
  • Zonisamide
  • Promethazine
  • Flecainide
  • Brivaracetam
  • Tetracaine
  • Amylocaine
  • Propoxycaine
  • Pramocaine
  • Pentoxyverine
  • Parachlorophenol
  • Dichlorobenzyl alcohol
  • Bioallethrin
  • Fish oil
Diseases
GWAS
  • Height ( 28552196 31562340)
  • Hip circumference adjusted for BMI ( 34021172)
Interacting Genes 10 interacting genes: CALM1 DLG1 DLG2 DLG3 ERBIN PATJ SLC9A3R1 SNTA1 SNTB1 SNTB2
Entrez ID 6329
HPRD ID 04912
Ensembl ID ENSG00000007314
Uniprot IDs P35499
PDB IDs 6AGF 6MBA 6MC9
Enriched GO Terms of Interacting Partners?
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