SC5D and UBE4A

		SC5D	UBE4A
Description		sterol-C5-desaturase	ubiquitination factor E4A
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Ubiquitin Ligase Complex Nucleus Cytoplasm
	Molecular Function	C-5 Sterol Desaturase Activity Iron Ion Binding Oxidoreductase Activity Delta7-sterol 5(6)-desaturase Activity	Protein Binding Ubiquitin-ubiquitin Ligase Activity
	Biological Process	Lipid Metabolic Process Sterol Biosynthetic Process Cholesterol Biosynthetic Process Via Desmosterol Cholesterol Biosynthetic Process Via Lathosterol	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway
Pathways		Activation of gene expression by SREBF (SREBP) Cholesterol biosynthesis via desmosterol Cholesterol biosynthesis via lathosterol	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Celiac disease and Rheumatoid arthritis ( 26546613) Fat distribution (HIV) ( 21897333)
Interacting Genes		7 interacting genes: CGREF1 FRMD5 RPS25 SCN4B SLC19A2 UBE4A VGLL1	14 interacting genes: CASP6 EPHA2 GZMB IP6K1 MAVS PTTG1 RSAD2 SC5D SLA UBE2D1 UBE2D2 UBE2D3 UBE2D4 VCP
Entrez ID		6309	9354
HPRD ID		09078	06793
Ensembl ID		ENSG00000109929	ENSG00000110344
Uniprot IDs		A0A024R3G4 O75845	Q14139
PDB IDs			1WGM
Enriched GO Terms of Interacting Partners?
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