USP22 and AASDHPPT

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		USP22	AASDHPPT
Description		ubiquitin specific peptidase 22	aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
Image		No pdb structure
GO Annotations	Cellular Component	SAGA Complex Nucleoplasm	Cytosol Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding H4 Histone Acetyltransferase Activity Enzyme Binding Nuclear Receptor Coactivator Activity	Magnesium Ion Binding Protein Binding Holo-[acyl-carrier-protein] Synthase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Cell Cycle Embryo Development Ending In Birth Or Egg Hatching Histone Ubiquitination Histone Deubiquitination Protein Deubiquitination Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Mitotic Cell Cycle	Pantothenate Metabolic Process Protein Phosphopantetheinylation Lysine Biosynthetic Process Via Aminoadipic Acid
Pathways		HATs acetylate histones Ub-specific processing proteases	Vitamin B5 (pantothenate) metabolism
Drugs
Diseases
GWAS		Body mass index ( 26426971) Mosquito bite size ( 28199695)	Coronary artery disease in type 1 diabetes ( 32077919) Upper eyelid morphology ( 29921221)
Interacting Genes		17 interacting genes: AASDHPPT ATXN7 ATXN7L3 B9D1 BAG4 H2AC20 H2BC21 HEXA MRPL10 MRPL44 MTUS2 PSME1 PTGS2 RCAN1 SCFD1 SIRT1 UBC	6 interacting genes: CRX EFHC2 MDFI SIAH1 TRAF2 USP22
Entrez ID		23326	60496
HPRD ID		19411	09675
Ensembl ID		ENSG00000124422	ENSG00000149313
Uniprot IDs		Q9UPT9	Q9NRN7
PDB IDs			2BYD 2C43 2CG5
Enriched GO Terms of Interacting Partners?
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