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RASA1 and HSPD1
Number of citations of the paper that reports this interaction (PubMedID
1347942
)
19
Data Source:
HPRD
(in vivo)
RASA1
HSPD1
Description
RAS p21 protein activator 1
heat shock protein family D (Hsp60) member 1
Image
GO Annotations
Cellular Component
Ruffle
Cytoplasm
Cytosol
Plasma Membrane
Extracellular Space
Cytoplasm
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Early Endosome
Peroxisomal Matrix
Rough Endoplasmic Reticulum
Cytosol
Plasma Membrane
Clathrin-coated Pit
Cell Surface
Membrane
Mitochondrial Crista
Coated Vesicle
Secretory Granule
Golgi Cisterna
Protein-containing Complex
Zymogen Granule
Membrane Raft
Lipopolysaccharide Receptor Complex
Extracellular Exosome
Sperm Midpiece
Molecular Function
Phosphotyrosine Residue Binding
GTPase Activity
GTPase Activator Activity
Signaling Receptor Binding
Protein Binding
Potassium Channel Inhibitor Activity
GTPase Binding
Lipopolysaccharide Binding
P53 Binding
DNA Replication Origin Binding
Single-stranded DNA Binding
RNA Binding
Double-stranded RNA Binding
Protein Binding
ATP Binding
High-density Lipoprotein Particle Binding
Isomerase Activity
ATP Hydrolysis Activity
Enzyme Binding
Ubiquitin Protein Ligase Binding
Apolipoprotein Binding
Apolipoprotein A-I Binding
Unfolded Protein Binding
Chaperone Binding
Modification-dependent Protein Binding
Biological Process
Mitotic Cytokinesis
Vasculogenesis
Negative Regulation Of Cell-matrix Adhesion
Negative Regulation Of Cell Adhesion
Signal Transduction
Regulation Of Cell Shape
Regulation Of Actin Filament Polymerization
Intracellular Signal Transduction
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of GTPase Activity
Negative Regulation Of Ras Protein Signal Transduction
Ephrin Receptor Signaling Pathway
Blood Vessel Morphogenesis
Regulation Of RNA Metabolic Process
Response To Hypoxia
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell
Response To Ischemia
Protein Folding
'de Novo' Protein Folding
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Unfolded Protein
Apoptotic Mitochondrial Changes
Response To Cold
Response To Xenobiotic Stimulus
Response To Activity
Response To Lipopolysaccharide
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Response To ATP
Mitochondrial Unfolded Protein Response
Cellular Response To Heat
Protein Refolding
B Cell Proliferation
T Cell Activation
B Cell Activation
Response To Cocaine
Response To Hydrogen Peroxide
Positive Regulation Of Macrophage Activation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Response To Estrogen
Adhesion Of Symbiont To Host
Protein Import Into Mitochondrial Intermembrane Space
Isotype Switching To IgG Isotypes
Positive Regulation Of Inflammatory Response
Protein Stabilization
Positive Regulation Of T Cell Activation
Chaperone-mediated Protein Complex Assembly
Response To Glucocorticoid
Protein Maturation
Biological Process Involved In Interaction With Symbiont
Negative Regulation Of Apoptotic Process In Bone Marrow Cell
Cellular Response To Interleukin-7
Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways
Downstream signal transduction
EPHB-mediated forward signaling
EPHB-mediated forward signaling
VEGFR2 mediated cell proliferation
Regulation of RAS by GAPs
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
Mitochondrial protein import
Mitochondrial protein import
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation
Drugs
Copper
Diseases
GWAS
Chronotype (
30696823
)
Macular thickness (
30535121
)
Major depressive disorder (
23377640
)
Openness (
21173776
)
Prostate cancer aggressiveness (
25939597
)
Type 2 diabetes (
30297969
)
Autism spectrum disorder or schizophrenia (
28540026
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Cortical thickness (MOSTest) (
32665545
)
Schizophrenia (
25056061
29483656
)
Subcortical volume (min-P) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
96 interacting genes:
ABL1
AFAP1L2
ALK
ANXA6
APC
APP
AR
ARHGAP1
ARHGAP5
AURKA
AURKB
BBS10
BCL10
BCR
BIRC5
BMPR1A
BUB1
CASP3
CASP7
CAV2
CD5
CDKN2A
CSF1R
CSK
DCC
DLC1
DNAJA3
DOK1
DOK2
DOK4
EGFR
EIF1
EPHA2
EPHB2
EPHB3
ERBB2
ERBB3
ERBB4
EZH2
FES
FGFR1
G3BP1
GAB1
GMCL1
GRB2
HCK
HRAS
HSPD1
HTT
IGF1R
INSR
KDR
KHDRBS1
KIT
LCK
LYN
MAGI1
MAP4K4
MET
MLH3
NCK1
NRAS
NTRK1
OLIG1
PAG1
PDE6D
PDGFRB
PIK3R1
PMS2
PTK2B
PTPRC
PTPRJ
PXN
RAB5A
RACK1
RAP1A
RB1
SERPINA4
SHC1
SLC9A2
SMAD2
SOCS3
SPSB1
SRC
STAU1
STK11
SYK
SYN1
TRMT2A
WWP1
WWP2
XRCC6
YES1
ZAP70
ZNF366
ZNF579
61 interacting genes:
ALDH2
APP
BAK1
BRCA1
CA2
CASP3
CASP6
CASP9
CEP70
CLEC7A
CLU
CYSRT1
DHFR
DUX4
ERBB2
ERG
FAM107A
FHIT
GLI2
H2BC21
HSPE1
ITGA3
ITGB1
KCTD10
KRT31
KRT34
KRT40
KRTAP10-3
KRTAP10-8
KRTAP5-9
LINC01554
LRRK2
LZTS2
MAPK6
MCPH1
MGAT3
MOB4
NOS1AP
NOTCH2NLA
NR3C1
OGT
PLCG2
PLG
PPP2R1A
PPP2R1B
PRKACA
PRNP
PTEN
PTPN11
RASA1
RGS20
SAMD3
SF3B1
SUMO2
SUMO4
SUPT6H
TLR1
TMCC2
TRIM63
UBASH3A
YWHAG
Entrez ID
5921
3329
HPRD ID
00745
00318
Ensembl ID
ENSG00000145715
ENSG00000144381
Uniprot IDs
P20936
Q59GK3
A0A024R3X4
P10809
PDB IDs
1WER
1WQ1
2GQI
2GSB
2J05
2J06
2M51
4FSS
6PXB
6PXC
6WAX
6WAY
4PJ1
6HT7
6MRC
6MRD
7AZP
Enriched GO Terms of Interacting Partners
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