RAP1GAP and MEX3B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAP1GAP	MEX3B
Description		RAP1 GTPase activating protein	mex-3 RNA binding family member B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Early Endosome Cytosol Membrane Axon Dendrite Neuronal Cell Body	P-body Nucleoplasm Cytosol
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding Small GTPase Binding Protein Homodimerization Activity	RNA Binding Calcium Ion Binding
	Biological Process	Adaptive Immune Response Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Negative Regulation Of Neuron Differentiation Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity Negative Regulation Of Microvillus Assembly Negative Regulation Of GTP Binding Negative Regulation Of Thyroid Gland Epithelial Cell Proliferation Cellular Response To Glial Cell Derived Neurotrophic Factor	Protein Phosphorylation Protein Autophosphorylation
Pathways		Rap1 signalling RET signaling
Drugs
Diseases
GWAS		Abdominal aortic calcification levels ( 31659325) Heel bone mineral density ( 30598549) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Liver enzyme levels ( 18940312) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Serum alkaline phosphatase levels ( 31666285)	Height ( 31562340) Macular thickness ( 30535121) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Post-traumatic stress disorder ( 24677629) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Tourette syndrome ( 30818990)
Interacting Genes		16 interacting genes: AFDN BRAF CDK1 CSNK1G2 DYNC1I1 GNAZ MAP1LC3B MAPK6 MEX3B PFN2 PLK1 PRKACA RALGDS RAP1A SDHB ZBTB12	8 interacting genes: ATP13A2 CPEB1 LINC00839 NUDT3 RAP1GAP SMAD4 SNUPN UBE2D3
Entrez ID		5909	84206
HPRD ID		02609	15256
Ensembl ID		ENSG00000076864	ENSG00000183496
Uniprot IDs		A0A024RAB5 P47736 X6R8W7	Q6ZN04
PDB IDs		1SRQ 3BRW
Enriched GO Terms of Interacting Partners?
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