RAB27A and MYRIP

Number of citations of the paper that reports this interaction (PubMedID 12590134)
15

Data Source:
HPRD (in vivo, in vitro)

		RAB27A	MYRIP
Description		RAB27A, member RAS oncogene family	myosin VIIA and Rab interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Extracellular Region Lysosome Late Endosome Golgi Apparatus Cytosol Apical Plasma Membrane Secretory Granule Dendrite Secretory Granule Membrane Multivesicular Body Membrane Weibel-Palade Body Melanosome Membrane Specific Granule Lumen Melanosome Extracellular Exosome Exocytic Vesicle	Exocyst Photoreceptor Outer Segment Transport Vesicle Cortical Actin Cytoskeleton Dense Core Granule Melanosome Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Actin Binding Protein Binding Zinc Ion Binding Myosin Binding Small GTPase Binding Protein Kinase A Binding
	Biological Process	Protein Targeting Exocytosis Blood Coagulation Positive Regulation Of Gene Expression Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion	Intracellular Protein Transport Positive Regulation Of Insulin Secretion
Pathways		Insulin processing Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Insulin processing
Drugs
Diseases
GWAS		Fractional exhaled nitric oxide levels ( 25431337) Glioma ( 30714141)	Acute lymphoblastic leukemia (childhood) ( 23007406) Information processing speed ( 21130836) Rapid automised naming of letters ( 30741946) Sleep-related phenotypes ( 17903308) Whole brain grey matter density ( 31530798)
Interacting Genes		29 interacting genes: ADRB2 APP BACE2 CEP126 COPS6 EEF1A1 ERG28 EXPH5 GDF9 GDI1 GZMB LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	5 interacting genes: C1orf216 MYO7A OIP5 RAB27A RAB27B
Entrez ID		5873	25924
HPRD ID		04845	14796
Ensembl ID		ENSG00000069974	ENSG00000170011
Uniprot IDs		A2RU94 P51159	Q8NFW9
PDB IDs		6HUF
Enriched GO Terms of Interacting Partners?
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