RAB27A and UNC13D

Number of citations of the paper that reports this interaction (PubMedID 14699162)
58

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		RAB27A	UNC13D
Description		RAB27A, member RAS oncogene family	unc-13 homolog D
Image			No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Extracellular Region Lysosome Late Endosome Golgi Apparatus Cytosol Apical Plasma Membrane Secretory Granule Dendrite Secretory Granule Membrane Multivesicular Body Membrane Weibel-Palade Body Melanosome Membrane Specific Granule Lumen Melanosome Extracellular Exosome Exocytic Vesicle	Extracellular Region Lysosome Late Endosome Cytosol Membrane Weibel-Palade Body Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Recycling Endosome Exocytic Vesicle
	Molecular Function	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding Small GTPase Binding Metal Ion Binding
	Biological Process	Protein Targeting Exocytosis Blood Coagulation Positive Regulation Of Gene Expression Antigen Processing And Presentation Melanocyte Differentiation Melanosome Localization Melanosome Transport Multivesicular Body Organization Cytotoxic T Cell Degranulation Natural Killer Cell Degranulation Positive Regulation Of Exocytosis Synaptic Vesicle Transport Positive Regulation Of Phagocytosis Multivesicular Body Sorting Pathway Complement-dependent Cytotoxicity Positive Regulation Of Regulated Secretory Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of Constitutive Secretory Pathway Exosomal Secretion	Granuloma Formation Germinal Center Formation Phagocytosis Regulation Of Mast Cell Degranulation Natural Killer Cell Degranulation Positive Regulation Of Exocytosis Defense Response To Virus Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Regulated Secretory Pathway
Pathways		Insulin processing Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Neutrophil degranulation
Drugs
Diseases
GWAS		Fractional exhaled nitric oxide levels ( 25431337) Glioma ( 30714141)	Apolipoprotein A1 levels ( 32203549) Asthma ( 34103634 32296059) Eosinophil counts ( 27863252) Major depressive disorder ( 27777418) Red cell distribution width ( 32888494) Systolic blood pressure ( 30578418) White matter hyperintensity burden ( 25663218)
Interacting Genes		29 interacting genes: ADRB2 APP BACE2 CEP126 COPS6 EEF1A1 ERG28 EXPH5 GDF9 GDI1 GZMB LRIF1 MLPH MYO5A MYRIP RABGGTB RBM48 RIMS1 RIMS2 RPH3A RPH3AL STX1A SYTL1 SYTL2 SYTL3 SYTL4 SYTL5 UNC13D ZBTB16	3 interacting genes: LMNA RAB27A RAB27B
Entrez ID		5873	201294
HPRD ID		04845	10598
Ensembl ID		ENSG00000069974	ENSG00000092929
Uniprot IDs		A2RU94 P51159	Q70J99
PDB IDs		6HUF
Enriched GO Terms of Interacting Partners?
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