MAP4K2 and NACAD

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

		MAP4K2	NACAD
Description		mitogen-activated protein kinase kinase kinase kinase 2	NAC alpha domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Basolateral Plasma Membrane	Nucleus Cytoplasm Nascent Polypeptide-associated Complex
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity Mitogen-activated Protein Kinase Kinase Kinase Binding Protein Serine Kinase Activity	Protein Binding Unfolded Protein Binding
	Biological Process	Protein Phosphorylation Vesicle Targeting Immune Response JNK Cascade Intracellular Signal Transduction Positive Regulation Of JUN Kinase Activity Innate Immune Response Positive Regulation Of JNK Cascade	Protein Targeting To Membrane
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Serum uric acid levels ( 32514006) Urate levels ( 21768215)	Eosinophil counts ( 32888494)
Interacting Genes		14 interacting genes: DEFB1 HNRNPA2B1 MAP2K4 MAP3K11 MCM3AP-AS1 NACAD POT1 PRDX4 RAB8A RELA SERPINA4 SNRNP35 TRAF2 XRCC6	10 interacting genes: AGTR1 CBLC HDAC6 MAP4K2 NR4A1 PTK2 RPS27 STAT3 TNNT1 YAE1
Entrez ID		5871	23148
HPRD ID		04408
Ensembl ID		ENSG00000168067	ENSG00000136274
Uniprot IDs		A0A024R567 Q12851	O15069
PDB IDs
Enriched GO Terms of Interacting Partners?
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