AASS

Description		aminoadipate-semialdehyde synthase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Corepressor Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Histone Binding Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Lysine Catabolic Process Lysine Biosynthetic Process Via Aminoadipic Acid Negative Regulation Of Histone Methylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine
Pathways		Lysine catabolism
Drugs		Glutamic acid NADH NADPH L-Saccharopine
Diseases
GWAS		Opioid dependence (time to event) ( 34124712)
Interacting Genes		7 interacting genes: ARF5 CCR6 CHCHD3 FSCN3 OGT PTPRZ1 WASL
Entrez ID		10157
HPRD ID		05489
Ensembl ID		ENSG00000008311
Uniprot IDs		A4D0W4 Q9UDR5
PDB IDs		5L76 5L78 5O1N 5O1O 5O1P
Enriched GO Terms of Interacting Partners?
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