PTN and ALK

  • Number of citations of the paper that reports this interaction (PubMedID 11278720)
  • 91
  • Data Source:
  • HPRD (in vivo, in vitro)

PTN

ALK

Description pleiotrophin ALK receptor tyrosine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Aluminium levels ( 26025379)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Blood protein levels ( 30072576 29875488)
  • Metabolite levels ( 23823483)
  • Neurociticism ( 29500382)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Schizophrenia ( 25056061 29483656)
  • Adiponectin levels (BMI-adjusted) ( 26299439)
  • Body mass index ( 25673413)
  • Body size at age 10 ( 32376654)
  • Carbamazepine-induced reaction with eosinophilia and systemic symptoms ( 31066027)
  • Carbamazepine-induced serious cutaneous adverse reaction ( 31066027)
  • Dentures ( 31235808)
  • Gestational age at birth (child effect) ( 31194736)
  • Glucose homeostasis traits ( 25524916)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Simvastatin-induced myopathy ( 31220337)
  • Spontaneous coronary artery dissection ( 32887874)
  • Systolic blood pressure ( 26969751)
  • Total cholesterol levels ( 33339817)
Interacting Genes 98 interacting genes: ACTB ALK APOBEC3G ARIH2 ARL15 ASPH ATP5F1C ATRX BAG6 BARD1 BCCIP BCL2L1 BLOC1S1 BMI1 BTBD2 C11orf58 C7orf25 CAAP1 CACNB4 CAPZB CDH10 CDK5RAP2 CGA CHD3 COX6C CRCT1 CRELD1 CSTA CYP2E1 DNAJB11 DUSP12 EIF3F EVA1A FEZ1 FTL GADD45A GADD45G GIPC2 GLYAT GPD1 GPRASP2 GSDME GSK3B GSTP1 GTF2F1 HGH1 HSPBAP1 ITSN2 KPNB1 LAMA4 LUC7L2 MAD2L1BP MKKS MLLT3 MRPL44 MYCBP NAP1L5 NCAN NEK6 NUDT21 P4HB PFDN1 PIAS4 PLXNB2 PMF1 PPP2CA PSMB10 PSMD11 PSMD2 PTPRS PTPRZ1 RACK1 RBM23 RIT1 RPLP1 SAT1 SDC1 SDC3 SGSM2 SGTA SLC25A36 SNCAIP SPIN1 SSR1 STC2 SUPT7L TAC3 TAF1D TBRG4 TOMM20 TP53BP2 TSC22D1 TXNDC9 UBQLN1 UBQLN4 UTP3 WASHC3 WFDC2 28 interacting genes: BIRC6 CLNS1A DLG2 DNMT3A DUSP19 ERBB2 HADHB HMGB1 IKBKG IRS1 JAK3 MDK MSH2 NLRC4 NPM1 PIK3R1 PLCG1 PPM1A PTN PTPRZ1 RASA1 SHC1 SHC3 SMC1A TNFRSF8 TSPAN16 TTC19 ZC3HC1
Entrez ID 5764 238
HPRD ID 01199 00104
Ensembl ID ENSG00000105894 ENSG00000171094
Uniprot IDs A0A024R778 P21246 B6D4Y2 Q9UM73
PDB IDs 2N6F 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4CCB 4CCU 4CD0 4CLI 4CLJ 4CMO 4CMT 4CMU 4CNH 4CTB 4CTC 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 4MKC 4TT7 4Z55 5A9U 5AA8 5AA9 5AAA 5AAB 5AAC 5FTO 5FTQ 5IMX 5IUG 5IUH 5IUI 5KZ0 5VZ5 6AT9 6CDT 6E0R 6EBW 6EDL 6MX8 7JY4 7JYR 7JYS 7JYT
Enriched GO Terms of Interacting Partners?
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