ALK and PPM1A

  • Number of citations of the paper that reports this interaction (PubMedID 28065597)
  • 37
  • Data Source:
  • BioGRID (two hybrid)

ALK

PPM1A

Description ALK receptor tyrosine kinase protein phosphatase, Mg2+/Mn2+ dependent 1A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adiponectin levels (BMI-adjusted) ( 26299439)
  • Body mass index ( 25673413)
  • Body size at age 10 ( 32376654)
  • Carbamazepine-induced reaction with eosinophilia and systemic symptoms ( 31066027)
  • Carbamazepine-induced serious cutaneous adverse reaction ( 31066027)
  • Dentures ( 31235808)
  • Gestational age at birth (child effect) ( 31194736)
  • Glucose homeostasis traits ( 25524916)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
  • Pre-treatment viral load in HIV-1 infection ( 31219150)
  • Simvastatin-induced myopathy ( 31220337)
  • Spontaneous coronary artery dissection ( 32887874)
  • Systolic blood pressure ( 26969751)
  • Total cholesterol levels ( 33339817)
  • Allergic rhinitis ( 22036096)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653)
  • Hair color ( 29662168)
  • Hip circumference adjusted for BMI ( 25673412)
  • Menarche (age at onset) ( 27182965)
  • Refractive error ( 32231278)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes 28 interacting genes: BIRC6 CLNS1A DLG2 DNMT3A DUSP19 ERBB2 HADHB HMGB1 IKBKG IRS1 JAK3 MDK MSH2 NLRC4 NPM1 PIK3R1 PLCG1 PPM1A PTN PTPRZ1 RASA1 SHC1 SHC3 SMC1A TNFRSF8 TSPAN16 TTC19 ZC3HC1 37 interacting genes: AATK AKT1 ALK CACNA1A CACNA1B CACNA1C CDC42BPA CDC42BPB CTNNB1 DVL1 DVL2 DVL3 EEF2 EGFR ERBB2 ERBB3 ERBB4 FGFR2 GRM3 HSPB1 IGF1R KDR LMTK2 MSN NR4A1 PAK1 PAK2 PIK3R1 PLK3 PRKAA1 PRKCA PRKCD PTK7 ROR2 RPLP0 SMAD2 SMAD3
Entrez ID 238 5494
HPRD ID 00104 16199
Ensembl ID ENSG00000171094 ENSG00000100614
Uniprot IDs B6D4Y2 Q9UM73 A0A024R6A5 B2R8E4 P35813
PDB IDs 2KUP 2KUQ 2XB7 2XBA 2XP2 2YFX 2YHV 2YJR 2YJS 2YS5 2YT2 3AOX 3L9P 3LCS 3LCT 4ANL 4ANQ 4ANS 4CCB 4CCU 4CD0 4CLI 4CLJ 4CMO 4CMT 4CMU 4CNH 4CTB 4CTC 4DCE 4FNW 4FNX 4FNY 4FNZ 4FOB 4FOC 4FOD 4JOA 4MKC 4TT7 4Z55 5A9U 5AA8 5AA9 5AAA 5AAB 5AAC 5FTO 5FTQ 5IMX 5IUG 5IUH 5IUI 5KZ0 5VZ5 6AT9 6CDT 6E0R 6EBW 6EDL 6MX8 7JY4 7JYR 7JYS 7JYT 1A6Q 3FXJ 3FXK 3FXL 3FXM 3FXO 4RA2 4RAF 4RAG 6B67
Enriched GO Terms of Interacting Partners?
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