PTH2R and DYNLT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PTH2R	DYNLT1
Description		parathyroid hormone 2 receptor	dynein light chain Tctex-type 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Parathyroid Hormone Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Hormone Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Dynein Intermediate Chain Binding
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus
Pathways		Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Neutrophil degranulation
Drugs		Parathyroid hormone
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anthropometric traits ( 30576415) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) Metabolite levels ( 23823483) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744)
Interacting Genes		6 interacting genes: CALM1 DYNLT1 GRHPR HMG20A PTH PTH2	57 interacting genes: ACAT2 ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 CRHBP DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 ERO1A FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PRKN PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RPS6KA2 RRAGA SDCBP SIRPA SVIL SYNJ2 TCEANC TMEM143 TROAP TUBA3C TXN UXT VDAC1 XRN2
Entrez ID		5746	6993
HPRD ID		03276	15987
Ensembl ID		ENSG00000144407	ENSG00000146425
Uniprot IDs		B4DFN8 P49190	P63172
PDB IDs			5JPW
Enriched GO Terms of Interacting Partners?
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