DYNLT1 and KLK15

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		DYNLT1	KLK15
Description		dynein light chain Tctex-type 1	kallikrein related peptidase 15
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Golgi Apparatus Spindle Cytoplasmic Dynein Complex Cytoplasmic Microtubule Lamellipodium Secretory Granule Lumen Neuronal Cell Body Host Cell Axonal Growth Cone Secretory Vesicle Ficolin-1-rich Granule Lumen	Extracellular Region Secretory Granule
	Molecular Function	Protein Binding Protein C-terminus Binding Identical Protein Binding Dynein Intermediate Chain Binding	Serine-type Endopeptidase Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Establishment Of Mitotic Spindle Orientation Microtubule-based Movement Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Dendrite Development Intracellular Transport Of Viral Protein In Host Cell Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of Mitochondrial Membrane Permeability Regulation Of GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Negative Regulation Of Cell Death Axon Development Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Proteolysis
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Celiac disease ( 23936387) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Prostate-specific antigen levels ( 25434496)
Interacting Genes		57 interacting genes: ACAT2 ACOX2 ACTN1 APP ARID4B BAG3 BMPR2 CCDC68 CRHBP DDX54 DHX33 DNAJA2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 DYNC1I2 DYNLT2B DYNLT3 ERO1A FXR2 HAVCR1 HSPB7 HSPB9 ILF2 KIF2A KLK15 LNX1 NHSL2 NTAQ1 NUP153 NUP62 OLFM3 PELO PITX2 PRKN PSMA1 PTGES3L-AARSD1 PTH2R PVR RAD21 RBM14 RPS6KA2 RRAGA SDCBP SIRPA SVIL SYNJ2 TCEANC TMEM143 TROAP TUBA3C TXN UXT VDAC1 XRN2	4 interacting genes: DYNLT1 HOOK2 KRTAP10-3 TRIP6
Entrez ID		6993	55554
HPRD ID		15987	07490
Ensembl ID		ENSG00000146425	ENSG00000174562
Uniprot IDs		P63172	A0A6B7HBY5 M0R0D7 Q6UBM2 Q9H2R5
PDB IDs		5JPW
Enriched GO Terms of Interacting Partners?
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