PTGER1 and PTGFR

Number of citations of the paper that reports this interaction (PubMedID 8253813)
51

Data Source:
HPRD (in vivo)

		PTGER1	PTGFR
Description		prostaglandin E receptor 1	prostaglandin F receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding	Prostaglandin F Receptor Activity
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipopolysaccharide Negative Regulation Of Gastric Emptying	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus
Pathways		Prostanoid ligand receptors G alpha (q) signalling events	Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Bupivacaine Carboprost tromethamine Alprostadil Bimatoprost Dinoprostone Misoprostol Iloprost Limaprost	Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS			Bipolar disorder ( 22182935) Depression in multiple sclerosis (post-diagnosis) ( 33296963) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)
Interacting Genes		5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR	12 interacting genes: AGTR1 CTH FPGT GTPBP4 IKBKE NOC2L PHOX2B PTGDS PTGER1 PTGER2 PTGES2 PTPRT
Entrez ID		5731	5737
HPRD ID		08903	08988
Ensembl ID		ENSG00000160951	ENSG00000122420
Uniprot IDs		P34995	P43088
PDB IDs
Enriched GO Terms of Interacting Partners?
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