ADAMTSL3 and EFL1

		ADAMTSL3	EFL1
Description		ADAMTS like 3	elongation factor like GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Intracellular Membrane-bounded Organelle	Cytosol Ribonucleoprotein Complex
	Molecular Function	Metalloendopeptidase Activity Protein Binding	Translation Elongation Factor Activity GTPase Activity GTP Binding Ribosome Binding
	Biological Process	Extracellular Matrix Organization	Translational Elongation Mature Ribosome Assembly GTP Metabolic Process
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins
Drugs			S-(Methylmercury)-L-Cysteine Deoxycholic acid Guanosine-5'-Diphosphate
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 28724990) Asthma ( 34103634 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 30804561 33909500) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 20881960 25282103 25429064 19343178 23563607 31562340 18391950 18391951 18391952 20397748 33713608 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hip index ( 34021172) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 34021172 26785701 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Alzheimer's disease ( 33654092)
Interacting Genes		21 interacting genes: ALPK3 BNC1 CYSRT1 EFL1 GLRX3 GOLGA2P10 HDGFL3 IDH3A KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA RAMAC	3 interacting genes: ADAMTSL3 LINC00839 SBDS
Entrez ID		57188	79631
HPRD ID		12426	07812
Ensembl ID		ENSG00000156218	ENSG00000140598
Uniprot IDs		P82987	Q7Z2Z2
PDB IDs			5ANB 5ANC
Enriched GO Terms of Interacting Partners?
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