ADAMTSL3 and KRTAP10-6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ADAMTSL3	KRTAP10-6
Description		ADAMTS like 3	keratin associated protein 10-6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Intracellular Membrane-bounded Organelle	Cytosol Keratin Filament
	Molecular Function	Metalloendopeptidase Activity Protein Binding	Protein Binding
	Biological Process	Extracellular Matrix Organization
Pathways		Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Keratinization
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 28724990) Asthma ( 34103634 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 30804561 33909500) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 21998595 28552196 20881960 25282103 25429064 19343178 23563607 31562340 18391950 18391951 18391952 20397748 33713608 20189936) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hip index ( 34021172) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 28991256 25056061 29483656 30285260) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28552196 34021172 26785701 25673412 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		21 interacting genes: ALPK3 BNC1 CYSRT1 EFL1 GLRX3 GOLGA2P10 HDGFL3 IDH3A KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA RAMAC	73 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-5 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-9 LCE1E LCE1F LCE2C LCE2D LCE3B LCE3E LCE4A MFSD3 MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1
Entrez ID		57188	386674
HPRD ID		12426	11192
Ensembl ID		ENSG00000156218	ENSG00000188155
Uniprot IDs		P82987	P60371
PDB IDs
Enriched GO Terms of Interacting Partners?
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