PRSS2 and CSN1S1

Number of citations of the paper that reports this interaction (PubMedID 20304780)
50

Data Source:
BioGRID (enzymatic study)

		PRSS2	CSN1S1
Description		serine protease 2	casein alpha s1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Azurophil Granule Lumen	Extracellular Region Extracellular Space
	Molecular Function	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Serine-type Peptidase Activity	Protein Binding
	Biological Process	Proteolysis Digestion Antimicrobial Humoral Response Extracellular Matrix Disassembly Positive Regulation Of Cell Growth Collagen Catabolic Process Positive Regulation Of Cell Adhesion	Response To Estradiol Response To Progesterone Response To Dehydroepiandrosterone Response To 11-deoxycorticosterone
Pathways		Collagen degradation Alpha-defensins Activation of Matrix Metalloproteinases Neutrophil degranulation Antimicrobial peptides	Miscellaneous transport and binding events
Drugs		Monoisopropylphosphorylserine O-Benzylsulfonyl-Serine Benzylamine Benzamidine Phosphorylisopropane Phenethylamine 3-Phenylpropylamine
Diseases
GWAS		Blood protein levels ( 29875488) Pancreatitis ( 23143602)
Interacting Genes		9 interacting genes: APP BPI CSN1S1 DMBT1 GLP1R MKKS MMP9 SERPINA1 SLPI	11 interacting genes: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 STK4 TOLLIP TTBK1 UBQLN2
Entrez ID		5645	1446
HPRD ID		03335	00280
Ensembl ID		ENSG00000275896	ENSG00000126545
Uniprot IDs		A6XMV9 P07478 Q5NV56 Q6PK75	P47710
PDB IDs
Enriched GO Terms of Interacting Partners?
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