CSN1S1 and PRSS2

Number of citations of the paper that reports this interaction (PubMedID 20304780)
50

Data Source:
BioGRID (enzymatic study)

		CSN1S1	PRSS2
Description		casein alpha s1	serine protease 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space Extracellular Matrix Azurophil Granule Lumen
	Molecular Function	Protein Binding	Metalloendopeptidase Activity Serine-type Endopeptidase Activity Calcium Ion Binding Protein Binding Serine-type Peptidase Activity
	Biological Process	Response To Estradiol Response To Progesterone Response To Dehydroepiandrosterone Response To 11-deoxycorticosterone	Proteolysis Digestion Antimicrobial Humoral Response Extracellular Matrix Disassembly Positive Regulation Of Cell Growth Collagen Catabolic Process Positive Regulation Of Cell Adhesion
Pathways		Miscellaneous transport and binding events	Collagen degradation Alpha-defensins Activation of Matrix Metalloproteinases Neutrophil degranulation Antimicrobial peptides
Drugs			Monoisopropylphosphorylserine O-Benzylsulfonyl-Serine Benzylamine Benzamidine Phosphorylisopropane Phenethylamine 3-Phenylpropylamine
Diseases
GWAS			Blood protein levels ( 29875488) Pancreatitis ( 23143602)
Interacting Genes		11 interacting genes: CSNK2A1 CSNK2B HTRA2 PARK7 PLK1 PPM1J PRSS2 STK4 TOLLIP TTBK1 UBQLN2	9 interacting genes: APP BPI CSN1S1 DMBT1 GLP1R MKKS MMP9 SERPINA1 SLPI
Entrez ID		1446	5645
HPRD ID		00280	03335
Ensembl ID		ENSG00000126545	ENSG00000275896
Uniprot IDs		P47710	A6XMV9 P07478 Q5NV56 Q6PK75
PDB IDs
Enriched GO Terms of Interacting Partners?
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