NXT2 and PKM

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		NXT2	PKM
Description		nuclear transport factor 2 like export factor 2	pyruvate kinase M1/2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Nuclear Pore Central Transport Channel Perinuclear Region Of Cytoplasm	Extracellular Region Nucleus Cytoplasm Mitochondrion Rough Endoplasmic Reticulum Cytosol Cilium Vesicle Secretory Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Magnesium Ion Binding RNA Binding MRNA Binding Pyruvate Kinase Activity Protein Binding ATP Binding Kinase Activity MHC Class II Protein Complex Binding Potassium Ion Binding Cadherin Binding
	Biological Process	Protein Import Into Nucleus Nucleocytoplasmic Transport MRNA Transport	Glycolytic Process Programmed Cell Death Cellular Response To Insulin Stimulus Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Cytoplasmic Translation
Pathways			Neutrophil degranulation
Drugs			Pyruvic acid L-Phospholactate 2-Phosphoglycolic Acid 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine Copper Artenimol
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301)
Interacting Genes		24 interacting genes: APP CCDC102B CEP63 DDIT4L GOLGA2 GOLGA6L9 IKZF3 LNX1 NXF1 NXF2 NXF2B NXF3 PKM PTPN3 RASSF10 REL SRPK1 SRPK2 SSBP3 STAT3 TCF4 TRIM23 USP54 ZNF655	63 interacting genes: ANXA7 APP ARAF ARX AURKB CCR4 CDC25A CDK4 CDKN1A CTNNB1 DLC1 DUX4 EGLN3 ENO3 EPM2A EXOSC5 FGFR1 FXR1 FXR2 GRB7 HERC1 HIF1A HOXA1 HSP90AA1 HULC KPNA1 LINC01554 LMO7 LNX1 MAPK1 MDM2 MYL2 MYOC NAGK NDRG1 NXT2 OGT OLFM2 PAX8 PIN1 POLE2 PRKN PTEN RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 SUMO1 SUMO2 TERF1 TINF2 TK1 TRIM35 TRIM55 TRIM63 UBE3A UCHL5 USP7 YWHAQ
Entrez ID		55916	5315
HPRD ID		02264	01529
Ensembl ID		ENSG00000101888	ENSG00000067225
Uniprot IDs		Q9NPJ8	A0A024R5Z9 B4DNK4 P14618 V9HWB8
PDB IDs			1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG 4QG6 4QG8 4QG9 4QGC 4RPP 4WJ8 4YJ5 5X0I 5X1V 5X1W 6B6U 6GG3 6GG4 6GG5 6GG6 6JFB 6NU1 6NU5 6NUB 6TTF 6TTH 6TTI 6TTQ 6V74 6V75 6V76 6WP3 6WP4 6WP5 6WP6
Enriched GO Terms of Interacting Partners?
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