Description |
pyruvate kinase M1/2 |
hypoxia inducible factor 1 subunit alpha |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Pyruvic acid
- L-Phospholactate
- 2-Phosphoglycolic Acid
- 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
- 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
- 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
- Copper
- Artenimol
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Diseases |
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GWAS |
- Aspartate aminotransferase levels ( 33547301)
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Interacting Genes |
63 interacting genes:
ANXA7
APP
ARAF
ARX
AURKB
CCR4
CDC25A
CDK4
CDKN1A
CTNNB1
DLC1
DUX4
EGLN3
ENO3
EPM2A
EXOSC5
FGFR1
FXR1
FXR2
GRB7
HERC1
HIF1A
HOXA1
HSP90AA1
HULC
KPNA1
LINC01554
LMO7
LNX1
MAPK1
MDM2
MYL2
MYOC
NAGK
NDRG1
NXT2
OGT
OLFM2
PAX8
PIN1
POLE2
PRKN
PTEN
RAF1
RAP1B
RCC1
RELA
RPP14
SHBG
SMN1
SORBS2
SUMO1
SUMO2
TERF1
TINF2
TK1
TRIM35
TRIM55
TRIM63
UBE3A
UCHL5
USP7
YWHAQ
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127 interacting genes:
AKT1
APEX1
AR
ARNT
ARNT2
ARNTL
ATM
AURKA
BNIP3
CASR
CCND2
CDC34
CDK4
CDK6
CDKN2A
CDKN2B
CITED2
COPS5
CREB3L1
CREBBP
CSNK1D
CSNK2A1
CTNNB1
DAP3
E2F7
EAF2
EGLN1
EGLN2
EGLN3
EIF5A2
EP300
EPHA2
EPO
ESRRA
ESRRB
ESRRG
ETV4
F12
FBXO8
FGFR4
FZR1
GATA3
GLIS2
HDAC1
HDAC2
HDAC3
HDAC5
HIF1A-AS2
HIF1AN
HIF3A
HNF4A
HSP90AA1
IKBKG
ISG15
JUN
KPNA1
KPNA3
KPNA4
KPNA5
KPNA6
LATS2
LINC01139
LRRK2
MAFG
MAFK
MAP2K3
MAP2K5
MAPK1
MAPK3
MAX
MCL1
MCM7
MDM2
MTA1
MYC
NAA10
NAA11
NBN
NCOA1
NCOA2
NDN
NEDD8
NF2
NQO1
NR4A1
OS9
PER1
PGK1
PKM
PLD1
PLD2
PLK3
PRKACA
PSMA7
PTBP1
PTK6
RACGAP1
RACK1
RB1
RORA
RUNX2
RWDD3
SAT1
SEPTIN9
SIRT2
SMAD3
SNHG11
SP1
SSX4
STAT3
STK11
STUB1
SUCO
SUMO1
TEAD2
TP53
TSGA10
UBE2D1
UBE2I
USP19
USP20
USP28
USP7
VEGFA
VHL
VHLL
ZC3H12A
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Entrez ID |
5315 |
3091 |
HPRD ID |
01529 |
04517 |
Ensembl ID |
ENSG00000067225
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ENSG00000100644
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Uniprot IDs |
A0A024R5Z9
B4DNK4
P14618
V9HWB8
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D0VY79
Q16665
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PDB IDs |
1T5A
1ZJH
3BJF
3BJT
3G2G
3GQY
3GR4
3H6O
3ME3
3SRD
3SRF
3SRH
3U2Z
4B2D
4FXF
4FXJ
4G1N
4JPG
4QG6
4QG8
4QG9
4QGC
4RPP
4WJ8
4YJ5
5X0I
5X1V
5X1W
6B6U
6GG3
6GG4
6GG5
6GG6
6JFB
6NU1
6NU5
6NUB
6TTF
6TTH
6TTI
6TTQ
6V74
6V75
6V76
6WP3
6WP4
6WP5
6WP6
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1D7G
1H2K
1H2L
1H2M
1L3E
1L8C
1LM8
1LQB
2ILM
3HQR
3HQU
4AJY
4H6J
5JWP
5L9B
5L9V
5LA9
5LAS
6GFX
6GMR
6YW3
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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