Description |
pyruvate kinase M1/2 |
karyopherin subunit alpha 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Pyruvic acid
- L-Phospholactate
- 2-Phosphoglycolic Acid
- 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
- 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
- 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine
- Copper
- Artenimol
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Diseases |
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GWAS |
- Aspartate aminotransferase levels ( 33547301)
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- Calcium levels ( 20705733)
- LDL cholesterol ( 30275531)
- LDL cholesterol levels ( 28334899)
- Mean corpuscular hemoglobin ( 32888494)
- Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
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Interacting Genes |
63 interacting genes:
ANXA7
APP
ARAF
ARX
AURKB
CCR4
CDC25A
CDK4
CDKN1A
CTNNB1
DLC1
DUX4
EGLN3
ENO3
EPM2A
EXOSC5
FGFR1
FXR1
FXR2
GRB7
HERC1
HIF1A
HOXA1
HSP90AA1
HULC
KPNA1
LINC01554
LMO7
LNX1
MAPK1
MDM2
MYL2
MYOC
NAGK
NDRG1
NXT2
OGT
OLFM2
PAX8
PIN1
POLE2
PRKN
PTEN
RAF1
RAP1B
RCC1
RELA
RPP14
SHBG
SMN1
SORBS2
SUMO1
SUMO2
TERF1
TINF2
TK1
TRIM35
TRIM55
TRIM63
UBE3A
UCHL5
USP7
YWHAQ
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46 interacting genes:
ANP32A
ANP32B
ARNT
BCAR3
CD86
CDKN1B
CLK4
CRADD
CSE1L
ELAVL1
EPAS1
FOSL1
GOPC
GTF2IRD1
H2BC21
H3-4
HDAC6
HIF1A
IL1RAP
KPNB1
LEF1
LINC01554
LMO4
MACROD1
MDM2
NMNAT1
NOSIP
NUP50
NUP54
NUP62
OGT
ORC4
PAX5
PKM
POLR3C
RAG1
RANBP2
RUNX1T1
SENP2
SKP2
SRP19
STAT1
STAT3
TAF9
UBR5
USP1
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Entrez ID |
5315 |
3836 |
HPRD ID |
01529 |
02819 |
Ensembl ID |
ENSG00000067225
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ENSG00000114030
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Uniprot IDs |
A0A024R5Z9
B4DNK4
P14618
V9HWB8
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B3KXZ2
P52294
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PDB IDs |
1T5A
1ZJH
3BJF
3BJT
3G2G
3GQY
3GR4
3H6O
3ME3
3SRD
3SRF
3SRH
3U2Z
4B2D
4FXF
4FXJ
4G1N
4JPG
4QG6
4QG8
4QG9
4QGC
4RPP
4WJ8
4YJ5
5X0I
5X1V
5X1W
6B6U
6GG3
6GG4
6GG5
6GG6
6JFB
6NU1
6NU5
6NUB
6TTF
6TTH
6TTI
6TTQ
6V74
6V75
6V76
6WP3
6WP4
6WP5
6WP6
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2JDQ
3TJ3
4B18
6WX9
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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