G2E3 and WDR6

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		G2E3	WDR6
Description		G2/M-phase specific E3 ubiquitin protein ligase	WD repeat domain 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding Insulin Receptor Substrate Binding
	Biological Process	Apoptotic Process Protein Ubiquitination	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy TRNA Methylation Regulation Of Cell Cycle
Pathways			RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Cognitive decline (age-related) ( 28078323)	Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: LST1 RPS15 TRIM54 WDR6	6 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3 SCAP
Entrez ID		55632	11180
HPRD ID		13851	06912
Ensembl ID		ENSG00000092140	ENSG00000178252
Uniprot IDs		B4DL73 F5GX24 Q49AD9 Q7L622	A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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