WDR6 and G2E3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WDR6	G2E3
Description		WD repeat domain 6	G2/M-phase specific E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Nucleus Nucleolus Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding Insulin Receptor Substrate Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy TRNA Methylation Regulation Of Cell Cycle	Apoptotic Process Protein Ubiquitination
Pathways		RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Cognitive decline (age-related) ( 28078323)
Interacting Genes		6 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3 SCAP	4 interacting genes: LST1 RPS15 TRIM54 WDR6
Entrez ID		11180	55632
HPRD ID		06912	13851
Ensembl ID		ENSG00000178252	ENSG00000092140
Uniprot IDs		A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5	B4DL73 F5GX24 Q49AD9 Q7L622
PDB IDs
Enriched GO Terms of Interacting Partners?
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