WDR6 and CDC42EP4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WDR6	CDC42EP4
Description		WD repeat domain 6	CDC42 effector protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Endomembrane System Actin Cytoskeleton Microtubule Cytoskeleton Phagocytic Vesicle
	Molecular Function	RNA Binding Protein Binding Insulin Receptor Substrate Binding	RNA Binding Protein Binding Small GTPase Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Negative Regulation Of Autophagy TRNA Methylation Regulation Of Cell Cycle	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Cellular Response To Interferon-gamma
Pathways		RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle	CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Menarche (age at onset) ( 25231870) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: BRCA1 CDC42EP4 G2E3 GRIP1 PTPN3 SCAP	9 interacting genes: APP BRD2 CDC42 FAM9B LNX1 RHOQ SRPK2 TGFBR1 WDR6
Entrez ID		11180	23580
HPRD ID		06912	08383
Ensembl ID		ENSG00000178252	ENSG00000179604
Uniprot IDs		A0A087X295 B3KRR8 B4E256 E9PDU5 Q9H9M3 Q9NNW5	B2R6D8 Q9H3Q1
PDB IDs
Enriched GO Terms of Interacting Partners?
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