PPP6C and TIPRL

Number of citations of the paper that reports this interaction (PubMedID 24255178)
195

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		PPP6C	TIPRL
Description		protein phosphatase 6 catalytic subunit	TOR signaling pathway regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Cytosol	Cytosol
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Protein Dephosphorylation Innate Immune Response COPII Vesicle Coating	DNA Damage Checkpoint Signaling TOR Signaling Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Pulse pressure ( 27841878) Refractive error ( 32231278) Systolic blood pressure ( 27841878 30578418)	LDL cholesterol levels in HIV infection ( 33109212) Red cell distribution width ( 32888494)
Interacting Genes		7 interacting genes: IGBP1 NFKBIE PRKDC TGFBR1 TIPRL VAC14 ZNRF2	5 interacting genes: APP PPP2CB PPP4C PPP6C UFL1
Entrez ID		5537	261726
HPRD ID		02141	14608
Ensembl ID		ENSG00000119414	ENSG00000143155
Uniprot IDs		A0A024R861 O00743	O75663
PDB IDs			5D9G
Enriched GO Terms of Interacting Partners?
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