TIPRL and PPP4C

Number of citations of the paper that reports this interaction (PubMedID 16085932)
76

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TIPRL	PPP4C
Description		TOR signaling pathway regulator	protein phosphatase 4 catalytic subunit
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex
	Molecular Function	Protein Binding	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	DNA Damage Checkpoint Signaling TOR Signaling Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling
Pathways			Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212) Red cell distribution width ( 32888494)	Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: APP PPP2CB PPP4C PPP6C UFL1	21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6
Entrez ID		261726	5531
HPRD ID		14608	03615
Ensembl ID		ENSG00000143155	ENSG00000149923
Uniprot IDs		O75663	A0A024R625 P60510
PDB IDs		5D9G
Enriched GO Terms of Interacting Partners?
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