TIPRL and UFL1

Number of citations of the paper that reports this interaction (PubMedID 32545848)
8

Data Source:
BioGRID (two hybrid)

		TIPRL	UFL1
Description		TOR signaling pathway regulator	UFM1 specific ligase 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Protein-containing Complex Site Of Double-strand Break Neuron Projection
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding UFM1 Ligase Activity UFM1 Transferase Activity
	Biological Process	DNA Damage Checkpoint Signaling TOR Signaling Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity	Osteoblast Differentiation DNA Repair Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy Histone Modification Erythrocyte Differentiation Negative Regulation Of Protein Ubiquitination Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Localization Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Inflammatory Response Hematopoietic Stem Cell Differentiation Positive Regulation Of Glial Cell Proliferation Reticulophagy Protein Ufmylation Response To L-glutamate Negative Regulation Of IRE1-mediated Unfolded Protein Response Protein K69-linked Ufmylation
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212) Red cell distribution width ( 32888494)	Diastolic blood pressure ( 27841878) Headache ( 29397368) Migraine ( 27322543) Migraine without aura ( 27322543) Night sleep phenotypes ( 27126917) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Triglyceride levels ( 32203549) Walking pace ( 33128006)
Interacting Genes		5 interacting genes: APP PPP2CB PPP4C PPP6C UFL1	18 interacting genes: AHCY AKAP17A ATP4A CDK5RAP3 ENY2 FGB H2AC4 HINFP IRAK1BP1 IRF3 MT1M PPIL1 PTPRO TIPRL TP53 TSC22D3 UFC1 ZNF219
Entrez ID		261726	23376
HPRD ID		14608	11109
Ensembl ID		ENSG00000143155	ENSG00000014123
Uniprot IDs		O75663	O94874
PDB IDs		5D9G
Enriched GO Terms of Interacting Partners?
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