LIN7C and MPP2

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		LIN7C	MPP2
Description		lin-7 homolog C, crumbs cell polarity complex component	MAGUK p55 scaffold protein 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane Glutamatergic Synapse	Cytoplasm Cytoskeleton Postsynaptic Density Dendrite Membrane Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Protein Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Protein Homooligomerization Excitatory Postsynaptic Potential Long-term Synaptic Potentiation
Pathways		Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Bone mineral density (paediatric, skull) ( 24945404) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Feeling miserable ( 29500382) Feeling nervous ( 29500382) Hip circumference ( 25673412) Lumbar spine bone mineral density ( 22504420) Menarche (age at onset) ( 27182965) Morning person ( 30696823) Survival in pancreatic cancer ( 28470677)	Cognitive function ( 24684796)
Interacting Genes		11 interacting genes: ABCA1 BAIAP2 DNAJC5 HTR2C KCNJ12 MPP2 MPP3 MPP7 PALS1 PALS2 YES1	7 interacting genes: CSNK2B DLG1 ERBIN LIN7A LIN7B LIN7C PLK1
Entrez ID		55327	4355
HPRD ID		17279	02837
Ensembl ID		ENSG00000148943	ENSG00000108852
Uniprot IDs		Q9NUP9	A0A0A0MRU0 A0A0C4DH75 B4DRL7 B4DZ84 D3DX48 D3DX49 Q14168
PDB IDs		3LRA	2E7K
Enriched GO Terms of Interacting Partners?
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