MPP2 and LIN7A

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		MPP2	LIN7A
Description		MAGUK p55 scaffold protein 2	lin-7 homolog A, crumbs cell polarity complex component
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Postsynaptic Density Dendrite Membrane Dendritic Spine Dendritic Shaft	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse Extracellular Exosome MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane
	Molecular Function	Protein Binding	Protein Binding L27 Domain Binding
	Biological Process	Protein Homooligomerization Excitatory Postsynaptic Potential Long-term Synaptic Potentiation	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly Protein Localization To Basolateral Plasma Membrane
Pathways			Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Cognitive function ( 24684796)	Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)
Interacting Genes		7 interacting genes: CSNK2B DLG1 ERBIN LIN7A LIN7B LIN7C PLK1	24 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK CHRD DLG2 DLG3 DLG4 DNAJC5 ECM1 FAM9B GOLGA2 GRIN2B KCNJ12 MDFI MPP2 MPP3 MPP7 NOTCH2NLA PALS1 PALS2 SLC6A12 ZYX
Entrez ID		4355	8825
HPRD ID		02837	04542
Ensembl ID		ENSG00000108852	ENSG00000111052
Uniprot IDs		A0A0A0MRU0 A0A0C4DH75 B4DRL7 B4DZ84 D3DX48 D3DX49 Q14168	O14910
PDB IDs		2E7K
Enriched GO Terms of Interacting Partners?
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