MPP2 and LIN7C

Number of citations of the paper that reports this interaction (PubMedID 26186194)
524

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		MPP2	LIN7C
Description		MAGUK p55 scaffold protein 2	lin-7 homolog C, crumbs cell polarity complex component
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Postsynaptic Density Dendrite Membrane Dendritic Spine Dendritic Shaft	Cytoplasm Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Cytoskeletal Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding
	Biological Process	Protein Homooligomerization Excitatory Postsynaptic Potential Long-term Synaptic Potentiation	Morphogenesis Of An Epithelial Sheet Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane
Pathways			Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Cognitive function ( 24684796)	Bone mineral density (paediatric, skull) ( 24945404) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Feeling miserable ( 29500382) Feeling nervous ( 29500382) Hip circumference ( 25673412) Lumbar spine bone mineral density ( 22504420) Menarche (age at onset) ( 27182965) Morning person ( 30696823) Survival in pancreatic cancer ( 28470677)
Interacting Genes		7 interacting genes: CSNK2B DLG1 ERBIN LIN7A LIN7B LIN7C PLK1	11 interacting genes: ABCA1 BAIAP2 DNAJC5 HTR2C KCNJ12 MPP2 MPP3 MPP7 PALS1 PALS2 YES1
Entrez ID		4355	55327
HPRD ID		02837	17279
Ensembl ID		ENSG00000108852	ENSG00000148943
Uniprot IDs		A0A0A0MRU0 A0A0C4DH75 B4DRL7 B4DZ84 D3DX48 D3DX49 Q14168	Q9NUP9
PDB IDs		2E7K	3LRA
Enriched GO Terms of Interacting Partners?
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