PPP4C and TIPRL

Number of citations of the paper that reports this interaction (PubMedID 16085932)
76

Data Source:
BioGRID (affinity chromatography technology, pull down)

		PPP4C	TIPRL
Description		protein phosphatase 4 catalytic subunit	TOR signaling pathway regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Cytosol
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Protein Binding
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	DNA Damage Checkpoint Signaling TOR Signaling Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	LDL cholesterol levels in HIV infection ( 33109212) Red cell distribution width ( 32888494)
Interacting Genes		21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6	5 interacting genes: APP PPP2CB PPP4C PPP6C UFL1
Entrez ID		5531	261726
HPRD ID		03615	14608
Ensembl ID		ENSG00000149923	ENSG00000143155
Uniprot IDs		A0A024R625 P60510	O75663
PDB IDs			5D9G
Enriched GO Terms of Interacting Partners?
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